Top 50 genes most highly expressed by the nonclassical monocyte subset sorted according to decreasing absolute fold change values
| Gene name . | Fold change normalized to intermediate* . | |
|---|---|---|
| Classic . | Nonclassic . | |
| Complement component 1 q subcomponent-α polypeptide (C1QA) | −15.64 | 1.47 |
| Hairy and enhancer of split 4 (HES4) | −14.80 | 1.58 |
| Cyclin-dependent kinase inhibitor 1C (CDKN1C) | −14.06 | 1.62 |
| Complement component 1 q subcomponent-β polypeptide (C1QB) | −11.56 | 1.36 |
| ras homolog gene family member C (RHOC) | −8.63 | 1.25 |
| C-type lectin domain family 4 member F (CLEC4F) | −8.32 | 1.43 |
| Adenosine deaminase (ADA) | −7.05 | 1.63 |
| Transgelin (TAGLN) | −6.06 | 1.60 |
| Transcription factor 7-like 2 (TCF7L2) | −5.96 | 1.28 |
| CD79B antigen (CD79B) | −5.83 | 1.77 |
| Cathepsin L (CTSL) | −5.28 | 1.31 |
| Surfactant pulmonary-associated protein D (SFTPD) | −4.74 | 2.07 |
| ABI gene family member 3 (ABI3) | −4.65 | 1.08 |
| SET binding protein 1 (SETBP1) | −4.61 | 1.47 |
| Fibroblast growth factor receptor-like 1 (FGFRL1) | −4.54 | 1.19 |
| CD79B antigen (CD79B) | −4.31 | 1.48 |
| Sprouty-related EVH1 domain containing 1 (SPRED1) | −4.23 | 1.19 |
| Jun dimerization protein p21SNFT (SNFT) | −4.23 | 1.35 |
| Enah/Vasp-like (EVL) | −4.21 | 1.12 |
| Metastasis suppressor 1 (MTSS1) | −4.00 | 1.72 |
| SH2 domain containing 1B (SH2D1B) | −2.38 | 3.79 |
| Cytoplasmic FMR1 interacting protein 2 (CYFIP2) | −3.94 | 1.42 |
| Nasal embryonic LHRH factor (NELF) | −3.92 | 1.06 |
| Cbl-interacting protein Sts-1 (STS-1) | −3.83 | 1.18 |
| Sialic acid binding Ig-like lectin 10 (SIGLEC10) | −3.63 | 1.46 |
| CDC28 protein kinase regulatory subunit 1B (CKS1B) | −3.63 | 1.23 |
| Protein tyrosine phosphatase type IVA member 3 (PTP4A3) | −3.61 | 1.97 |
| LY6/PLAUR domain containing 2 (LYPD2) | −3.59 | 5.87 |
| SID1 transmembrane family member 2 (SIDT2) | −3.59 | 1.26 |
| Insulin-induced gene 1 (INSIG1) | −3.59 | 1.61 |
| Lymphotoxin-β (LTB) | −3.50 | 1.27 |
| 3′-Phosphoadenosine 5′-phosphosulfate synthase 2 (PAPSS2) | −3.41 | 1.38 |
| ATP-binding cassette subfamily C member 3 (ABCC3) | −3.41 | 1.79 |
| Caspase 5 apoptosis-related cysteine peptidase (CASP5) | −3.39 | 1.65 |
| Vitelline membrane outer layer 1 homolog (chicken; VMO1) | −1.35 | 3.28 |
| Heat shock 27kDa protein 1 (HSPB1) | −3.27 | 1.09 |
| Guanine nucleotide binding protein-γ transducing activity polypeptide 2 (GNGT2) | −3.26 | 1.16 |
| Heme oxygenase (decycling) 1 (HMOX1) | −3.25 | 1.34 |
| Related RAS viral (r-ras) oncogene homolog (RRAS) | −3.22 | 1.21 |
| Ring finger protein 122 (RNF122) | −3.21 | 1.59 |
| Cadherin-like 23 (CDH23) | −3.20 | 3.60 |
| Formin-like 2 (FMNL2) | −3.20 | 1.60 |
| Regulator of G-protein signalling 12 (RGS12) | −3.19 | 1.29 |
| Secretoglobin family 3A member 1 (SCGB3A1) | −3.17 | 2.07 |
| fer-1-like 3 myoferlin (C. elegans) (FER1L3) | −3.15 | 1.11 |
| Calmodulin-like 4 (CALML4) | −3.08 | 1.12 |
| Interferon-induced transmembrane protein 3 (IFITM3) | −3.07 | 1.03 |
| Creatine kinase brain (CKB) | −2.22 | 3.07 |
| Interferon-induced transmembrane protein 1 (IFITM1) | −3.04 | 1.30 |
| Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) | −2.99 | 1.22 |
| Gene name . | Fold change normalized to intermediate* . | |
|---|---|---|
| Classic . | Nonclassic . | |
| Complement component 1 q subcomponent-α polypeptide (C1QA) | −15.64 | 1.47 |
| Hairy and enhancer of split 4 (HES4) | −14.80 | 1.58 |
| Cyclin-dependent kinase inhibitor 1C (CDKN1C) | −14.06 | 1.62 |
| Complement component 1 q subcomponent-β polypeptide (C1QB) | −11.56 | 1.36 |
| ras homolog gene family member C (RHOC) | −8.63 | 1.25 |
| C-type lectin domain family 4 member F (CLEC4F) | −8.32 | 1.43 |
| Adenosine deaminase (ADA) | −7.05 | 1.63 |
| Transgelin (TAGLN) | −6.06 | 1.60 |
| Transcription factor 7-like 2 (TCF7L2) | −5.96 | 1.28 |
| CD79B antigen (CD79B) | −5.83 | 1.77 |
| Cathepsin L (CTSL) | −5.28 | 1.31 |
| Surfactant pulmonary-associated protein D (SFTPD) | −4.74 | 2.07 |
| ABI gene family member 3 (ABI3) | −4.65 | 1.08 |
| SET binding protein 1 (SETBP1) | −4.61 | 1.47 |
| Fibroblast growth factor receptor-like 1 (FGFRL1) | −4.54 | 1.19 |
| CD79B antigen (CD79B) | −4.31 | 1.48 |
| Sprouty-related EVH1 domain containing 1 (SPRED1) | −4.23 | 1.19 |
| Jun dimerization protein p21SNFT (SNFT) | −4.23 | 1.35 |
| Enah/Vasp-like (EVL) | −4.21 | 1.12 |
| Metastasis suppressor 1 (MTSS1) | −4.00 | 1.72 |
| SH2 domain containing 1B (SH2D1B) | −2.38 | 3.79 |
| Cytoplasmic FMR1 interacting protein 2 (CYFIP2) | −3.94 | 1.42 |
| Nasal embryonic LHRH factor (NELF) | −3.92 | 1.06 |
| Cbl-interacting protein Sts-1 (STS-1) | −3.83 | 1.18 |
| Sialic acid binding Ig-like lectin 10 (SIGLEC10) | −3.63 | 1.46 |
| CDC28 protein kinase regulatory subunit 1B (CKS1B) | −3.63 | 1.23 |
| Protein tyrosine phosphatase type IVA member 3 (PTP4A3) | −3.61 | 1.97 |
| LY6/PLAUR domain containing 2 (LYPD2) | −3.59 | 5.87 |
| SID1 transmembrane family member 2 (SIDT2) | −3.59 | 1.26 |
| Insulin-induced gene 1 (INSIG1) | −3.59 | 1.61 |
| Lymphotoxin-β (LTB) | −3.50 | 1.27 |
| 3′-Phosphoadenosine 5′-phosphosulfate synthase 2 (PAPSS2) | −3.41 | 1.38 |
| ATP-binding cassette subfamily C member 3 (ABCC3) | −3.41 | 1.79 |
| Caspase 5 apoptosis-related cysteine peptidase (CASP5) | −3.39 | 1.65 |
| Vitelline membrane outer layer 1 homolog (chicken; VMO1) | −1.35 | 3.28 |
| Heat shock 27kDa protein 1 (HSPB1) | −3.27 | 1.09 |
| Guanine nucleotide binding protein-γ transducing activity polypeptide 2 (GNGT2) | −3.26 | 1.16 |
| Heme oxygenase (decycling) 1 (HMOX1) | −3.25 | 1.34 |
| Related RAS viral (r-ras) oncogene homolog (RRAS) | −3.22 | 1.21 |
| Ring finger protein 122 (RNF122) | −3.21 | 1.59 |
| Cadherin-like 23 (CDH23) | −3.20 | 3.60 |
| Formin-like 2 (FMNL2) | −3.20 | 1.60 |
| Regulator of G-protein signalling 12 (RGS12) | −3.19 | 1.29 |
| Secretoglobin family 3A member 1 (SCGB3A1) | −3.17 | 2.07 |
| fer-1-like 3 myoferlin (C. elegans) (FER1L3) | −3.15 | 1.11 |
| Calmodulin-like 4 (CALML4) | −3.08 | 1.12 |
| Interferon-induced transmembrane protein 3 (IFITM3) | −3.07 | 1.03 |
| Creatine kinase brain (CKB) | −2.22 | 3.07 |
| Interferon-induced transmembrane protein 1 (IFITM1) | −3.04 | 1.30 |
| Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) | −2.99 | 1.22 |
Obtained by calculating the MFI values of classical or nonclassical relative to intermediate.