Top 50 genes most highly expressed by the classical monocyte subset sorted by decreasing absolute fold change values
| Gene name . | Fold change normalized to intermediate* . | |
|---|---|---|
| Classic . | Nonclassic . | |
| S100 calcium binding protein A12 (S100A12) | 13.76 | −2.35 |
| Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) | 13.27 | −2.38 |
| Peptidyl arginine deiminase type IV (PADI4) | 10.08 | −2.19 |
| Neuregulin 1 (NRG1) | 9.94 | −1.40 |
| mast cell-expressed membrane protein 1 (MCEMP1) | 9.93 | −2.93 |
| Thrombospondin 1 (THBS1) | 9.25 | −1.46 |
| Cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2) | 8.79 | −1.61 |
| Coagulation factor XIII A1 polypeptide (F13A1) | 8.14 | −1.53 |
| MOCO sulphurase C-terminal domain containing 1 (MOSC1) | 7.81 | −1.73 |
| Cytochrome P450 family 27 subfamily A polypeptide 1 (CYP27A1) | 7.61 | −2.22 |
| CD163 antigen (CD163) | 7.42 | −3.44 |
| Glutaminyl-peptide cyclotransferase (QPCT) | 7.31 | −2.32 |
| ADAM metallopeptidase domain 19 (ADAM19) | 7.28 | −1.54 |
| Asialoglycoprotein receptor 2 (ASGR2) | 6.82 | −1.89 |
| Ribonuclease RNase A family 2 (RNASE2) | 6.31 | −2.66 |
| Coagulation factor V (proaccelerin labile factor; F5) | 5.92 | −1.44 |
| Folate receptor 3 (gamma; FOLR3) | 5.82 | −2.32 |
| Ribonuclease RNase A family 4 (RNASE4) | 5.72 | −1.58 |
| Aldehyde dehydrogenase 1 family member A1 (ALDH1A1) | 5.70 | −2.51 |
| Endothelial differentiation sphingolipid G-protein-coupled receptor 3 (EDG3) | 5.57 | −1.25 |
| Prokineticin 2 (PROK2) | 5.52 | −1.87 |
| C-type lectin domain family 4 member D (CLEC4D) | 5.42 | −1.34 |
| S100 calcium binding protein A9 (calgranulin B; S100A9) | 5.38 | −2.03 |
| Oncostatin M (OSM) | 5.36 | −2.27 |
| Chondroitin sulfate proteoglycan 2 (CSPG2) | 5.34 | −3.98 |
| Lectin galactoside-binding soluble 2 (GALS2) | 5.33 | −2.51 |
| Angiogenin ribonuclease RNase A family 5 (ANG) | 5.26 | −2.14 |
| Vanin 2 (VNN2) | 5.21 | −1.34 |
| Epstein-Barr virus-induced gene 2 (EBI2) | 4.31 | −5.13 |
| Urotensin 2 (UTS2) | 5.06 | −1.75 |
| Ribonuclease P RNA component H1 (RPPH1) | 4.76 | −1.38 |
| Microsomal glutathione S-transferase 1 (MGST1) | 4.75 | −1.88 |
| Interleukin 8 (IL-8) | 4.74 | −1.08 |
| Chemokine C-C motif receptor 2 (CCR2) | 4.73 | −1.25 |
| Selectin L (SELL) | 4.68 | −1.84 |
| Dysferlin limb girdle muscular dystrophy 2B (DYSF) | 4.58 | −1.72 |
| Metallothionein 1F (MT1F) | 4.57 | −1.36 |
| CD14 antigen (CD14) | 4.54 | −4.29 |
| Ribonuclease RNase A family k6 (RNASE6) | 3.72 | −4.44 |
| Colony-stimulating factor 3 receptor (CSF3R) | 4.38 | −1.62 |
| Stabilin 1 (STAB1) | 2.55 | −4.35 |
| Cytochrome P450 family 1 subfamily B polypeptide 1 (CYP1B1) | 4.31 | −1.16 |
| Alcohol dehydrogenase iron containing 1 (ADHFE1) | 4.29 | −1.15 |
| Phospholipase A2 group VII (PLA2G7) | 4.27 | −2.98 |
| Matrix metallopeptidase 25 (MMP25) | 4.14 | −1.30 |
| Zinc finger protein 395 (ZNF395) | 4.11 | −1.57 |
| Solute carrier family 2 member 3 (SLC2A3) | 3.78 | −3.96 |
| Early growth response 1 (EGR1) | 3.79 | −2.26 |
| CKLF-like MARVEL transmembrane domain containing 2 (CMTM2) | 3.78 | −1.15 |
| CD9 antigen p24 (CD9) | 2.60 | −3.66 |
| Gene name . | Fold change normalized to intermediate* . | |
|---|---|---|
| Classic . | Nonclassic . | |
| S100 calcium binding protein A12 (S100A12) | 13.76 | −2.35 |
| Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) | 13.27 | −2.38 |
| Peptidyl arginine deiminase type IV (PADI4) | 10.08 | −2.19 |
| Neuregulin 1 (NRG1) | 9.94 | −1.40 |
| mast cell-expressed membrane protein 1 (MCEMP1) | 9.93 | −2.93 |
| Thrombospondin 1 (THBS1) | 9.25 | −1.46 |
| Cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2) | 8.79 | −1.61 |
| Coagulation factor XIII A1 polypeptide (F13A1) | 8.14 | −1.53 |
| MOCO sulphurase C-terminal domain containing 1 (MOSC1) | 7.81 | −1.73 |
| Cytochrome P450 family 27 subfamily A polypeptide 1 (CYP27A1) | 7.61 | −2.22 |
| CD163 antigen (CD163) | 7.42 | −3.44 |
| Glutaminyl-peptide cyclotransferase (QPCT) | 7.31 | −2.32 |
| ADAM metallopeptidase domain 19 (ADAM19) | 7.28 | −1.54 |
| Asialoglycoprotein receptor 2 (ASGR2) | 6.82 | −1.89 |
| Ribonuclease RNase A family 2 (RNASE2) | 6.31 | −2.66 |
| Coagulation factor V (proaccelerin labile factor; F5) | 5.92 | −1.44 |
| Folate receptor 3 (gamma; FOLR3) | 5.82 | −2.32 |
| Ribonuclease RNase A family 4 (RNASE4) | 5.72 | −1.58 |
| Aldehyde dehydrogenase 1 family member A1 (ALDH1A1) | 5.70 | −2.51 |
| Endothelial differentiation sphingolipid G-protein-coupled receptor 3 (EDG3) | 5.57 | −1.25 |
| Prokineticin 2 (PROK2) | 5.52 | −1.87 |
| C-type lectin domain family 4 member D (CLEC4D) | 5.42 | −1.34 |
| S100 calcium binding protein A9 (calgranulin B; S100A9) | 5.38 | −2.03 |
| Oncostatin M (OSM) | 5.36 | −2.27 |
| Chondroitin sulfate proteoglycan 2 (CSPG2) | 5.34 | −3.98 |
| Lectin galactoside-binding soluble 2 (GALS2) | 5.33 | −2.51 |
| Angiogenin ribonuclease RNase A family 5 (ANG) | 5.26 | −2.14 |
| Vanin 2 (VNN2) | 5.21 | −1.34 |
| Epstein-Barr virus-induced gene 2 (EBI2) | 4.31 | −5.13 |
| Urotensin 2 (UTS2) | 5.06 | −1.75 |
| Ribonuclease P RNA component H1 (RPPH1) | 4.76 | −1.38 |
| Microsomal glutathione S-transferase 1 (MGST1) | 4.75 | −1.88 |
| Interleukin 8 (IL-8) | 4.74 | −1.08 |
| Chemokine C-C motif receptor 2 (CCR2) | 4.73 | −1.25 |
| Selectin L (SELL) | 4.68 | −1.84 |
| Dysferlin limb girdle muscular dystrophy 2B (DYSF) | 4.58 | −1.72 |
| Metallothionein 1F (MT1F) | 4.57 | −1.36 |
| CD14 antigen (CD14) | 4.54 | −4.29 |
| Ribonuclease RNase A family k6 (RNASE6) | 3.72 | −4.44 |
| Colony-stimulating factor 3 receptor (CSF3R) | 4.38 | −1.62 |
| Stabilin 1 (STAB1) | 2.55 | −4.35 |
| Cytochrome P450 family 1 subfamily B polypeptide 1 (CYP1B1) | 4.31 | −1.16 |
| Alcohol dehydrogenase iron containing 1 (ADHFE1) | 4.29 | −1.15 |
| Phospholipase A2 group VII (PLA2G7) | 4.27 | −2.98 |
| Matrix metallopeptidase 25 (MMP25) | 4.14 | −1.30 |
| Zinc finger protein 395 (ZNF395) | 4.11 | −1.57 |
| Solute carrier family 2 member 3 (SLC2A3) | 3.78 | −3.96 |
| Early growth response 1 (EGR1) | 3.79 | −2.26 |
| CKLF-like MARVEL transmembrane domain containing 2 (CMTM2) | 3.78 | −1.15 |
| CD9 antigen p24 (CD9) | 2.60 | −3.66 |
Obtained by calculating the MFI values of classical or nonclassical relative to intermediate.