Results of Cox proportional hazard regression models evaluating the effects of various factors on mortality risk
| Independent variable* . | Full model . | Reduced model . | ||
|---|---|---|---|---|
| Adjusted hazard ratio (95% CI) . | P . | Adjusted hazard ratio (95% CI) . | P . | |
| Sex | ||||
| Male (ref) | 1.000 | |||
| Female | 1.030 (0.851-1.247) | .761 | ||
| Race | ||||
| White (ref) | 1.000 | |||
| Black | 0.997 (0.693-1.433) | .987 | ||
| Other | 0.875 (0.638-1.199) | .405 | ||
| Age group | ||||
| < 35 y (ref) | 1.000 | 1.000 | ||
| 35-54 y | 1.266 (0.974-1.646) | .078 | 1.258 (0.969-1.633) | .084 |
| > 54 | 2.648 (2.083-3.366) | < .0001 | 2.646 (2.086-3.356) | < .0001 |
| Time period of diagnosis | ||||
| 1992-1995 (ref) | 1.000 | 1.000 | ||
| 1996-2001 | 0.699 (0.544-0.899) | .005 | 0.694 (0.540-0.892) | .004 |
| 2002-2007 | 0.615 (0.479-0.788) | .0001 | 0.609 (0.475-0.781) | .0001 |
| Resident county | ||||
| Rural (ref) | 1.000 | |||
| Urban | 0.927 (0.650-1.322) | .677 | ||
| Region† | ||||
| East (ref) | 1.000 | |||
| Northern Plains | 1.169 (0.823-1.659) | .384 | ||
| Pacific Coast | 1.223 (0.914-1.636) | .176 | ||
| Southwest | 1.355 (0.893-2.057) | .154 | ||
| Independent variable* . | Full model . | Reduced model . | ||
|---|---|---|---|---|
| Adjusted hazard ratio (95% CI) . | P . | Adjusted hazard ratio (95% CI) . | P . | |
| Sex | ||||
| Male (ref) | 1.000 | |||
| Female | 1.030 (0.851-1.247) | .761 | ||
| Race | ||||
| White (ref) | 1.000 | |||
| Black | 0.997 (0.693-1.433) | .987 | ||
| Other | 0.875 (0.638-1.199) | .405 | ||
| Age group | ||||
| < 35 y (ref) | 1.000 | 1.000 | ||
| 35-54 y | 1.266 (0.974-1.646) | .078 | 1.258 (0.969-1.633) | .084 |
| > 54 | 2.648 (2.083-3.366) | < .0001 | 2.646 (2.086-3.356) | < .0001 |
| Time period of diagnosis | ||||
| 1992-1995 (ref) | 1.000 | 1.000 | ||
| 1996-2001 | 0.699 (0.544-0.899) | .005 | 0.694 (0.540-0.892) | .004 |
| 2002-2007 | 0.615 (0.479-0.788) | .0001 | 0.609 (0.475-0.781) | .0001 |
| Resident county | ||||
| Rural (ref) | 1.000 | |||
| Urban | 0.927 (0.650-1.322) | .677 | ||
| Region† | ||||
| East (ref) | 1.000 | |||
| Northern Plains | 1.169 (0.823-1.659) | .384 | ||
| Pacific Coast | 1.223 (0.914-1.636) | .176 | ||
| Southwest | 1.355 (0.893-2.057) | .154 | ||
Reference coding was used for each variable. The reference group for each variable was labeled with ref.
Region is defined as follows: East includes Connecticut, Atlanta (Metropolitan), and Rural Georgia; Northern Plains includes Detroit (Metropolitan) and Iowa; Pacific Coast includes San Francisco-Oakland, Hawaii, Seattle (Puget Sound), San Jose-Monterey, and Los Angeles; and Southwest includes New Mexico and Utah. Because no patients with APL were reported from Alaska during 1992-2007, the region of Alaska is not listed.