Association between activating KIR genes and risk for T-ALL in white
| Gene . | Patients (n = 30), n (%) . | Control subjects (n = 245), n (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|
| 2DS1 | 6 (20.0) | 102 (41.6) | 0.35 (0.14-0.89) | .027 |
| 2DS2 | 9 (30.0) | 138 (56.3) | 0.32 (0.15-0.75) | .009 |
| 2DS3 | 2 (6.8) | 83 (33.9) | 0.14 (0.03-0.60) | .008 |
| 2DS4* | 12 (40.0) | 139 (56.7) | 0.51 (0.23-1.10) | .086 |
| 2DS5 | 8 (26.7) | 104 (42.4) | 0.49 (0.21-1.15) | .100 |
| 3DS1 | 8 (26.7) | 101 (41.2) | 0.52 (0.22-1.21) | .130 |
| Gene . | Patients (n = 30), n (%) . | Control subjects (n = 245), n (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|
| 2DS1 | 6 (20.0) | 102 (41.6) | 0.35 (0.14-0.89) | .027 |
| 2DS2 | 9 (30.0) | 138 (56.3) | 0.32 (0.15-0.75) | .009 |
| 2DS3 | 2 (6.8) | 83 (33.9) | 0.14 (0.03-0.60) | .008 |
| 2DS4* | 12 (40.0) | 139 (56.7) | 0.51 (0.23-1.10) | .086 |
| 2DS5 | 8 (26.7) | 104 (42.4) | 0.49 (0.21-1.15) | .100 |
| 3DS1 | 8 (26.7) | 101 (41.2) | 0.52 (0.22-1.21) | .130 |
The prefix KIR is not shown with the gene names.
OR indicates odds ratio; and CI, confidence interval.
KIR2DS4 was considered absent when the PCR amplified only the 22-bp deleted amplicon. It was considered present when the nonmutant amplicon was observed on the gel with or without the mutant band.