Hemodynamic variables
. | Baseline . | Hemodilution . | 30 min after trauma . | 60 min after trauma . | 120 min after trauma . |
---|---|---|---|---|---|
HR, beats/min | |||||
Control | 86 ± 8 | 80 ± 6* | 120 ± 12 | 140 ± 23 | 155 ± 26 |
PCC35 | 82 ± 11 | 83 ± 8 | 94 ± 10† | 98 ± 10† | 93 ± 13† |
PCC50DIC− | 91 ± 6 | 85 ± 5 | 99 ± 17† | 94 ± 19† | 108 ± 18† |
PCC50DIC+ | 85 ± 9 | 76 ± 4*§ | 133 ± 22‡§ | 132 ± 24‡§ | 165 ± 21‡§ |
MAP, mmHg | |||||
Control | 96 ± 11 | 86 ± 7* | 44 ± 13 | 40 ± 11 | 30 ± 8 |
PCC35 | 94 ± 10 | 87 ± 10* | 56 ± 18 | 66 ± 13† | 65 ± 12† |
PCC50DIC− | 88 ± 9 | 84 ± 5 | 61 ± 9† | 69 ± 9† | 68 ± 5† |
PCC50DIC+ | 87 ± 11 | 78 ± 4§ | 35 ± 10‡§ | 31 ± 14‡§ | 26 ± 13‡§ |
CVP, mmHg | |||||
Control | 7 ± 1 | 7 ± 1 | 4 ± 1 | 3 ± 1 | 2 ± 1 |
PCC35 | 7 ± 2 | 8 ± 1 | 4 ± 1 | 4 ± 2 | 5 ± 1† |
PCC50DIC− | 6 ± 2 | 8 ± 1 | 5 ± 1† | 5 ± 1† | 6 ± 1† |
PCC50DIC+ | 6 ± 1 | 8 ± 1* | 4 ± 1 | 5 ± 1 | 5 ± 1† |
MPAP, mmHg | |||||
Control | 18 ± 2 | 18 ± 2 | 11 ± 3 | 10 ± 2 | 9 ± 2 |
PCC35 | 17 ± 3 | 20 ± 3 | 12 ± 4 | 13 ± 3 | 13 ± 5† |
PCC50DIC− | 17 ± 2 | 18 ± 2* | 15 ± 4 | 15 ± 1† | 16 ± 2† |
PCC50DIC+ | 18 ± 5 | 17 ± 2 | 13 ± 4 | 11 ± 2§ | 11 ± 1§ |
CO, L/min | |||||
Control | 4.2 ± 0.5 | 4.3 ± 0.4 | 3.0 ± 1.2 | 2.4 ± 1.3 | 1.3 ± 0.5 |
PCC35 | 4.3 ± 0.4 | 4.4 ± 0.5 | 3.5 ± 0.4 | 3.3 ± 0.4† | 3.3 ± 0.5† |
PCC50DIC− | 3.9 ± 0.4 | 4.3 ± 0.6 | 3.7 ± 0.7 | 3.7 ± 0.6† | 3.2 ± 0.6† |
PCC50DIC+ | 4.1 ± 0.5 | 3.9 ± 0.2 | 2.6 ± 0.9 | 2.4 ± 0.9 | 1.7 ± 0.2‡§ |
. | Baseline . | Hemodilution . | 30 min after trauma . | 60 min after trauma . | 120 min after trauma . |
---|---|---|---|---|---|
HR, beats/min | |||||
Control | 86 ± 8 | 80 ± 6* | 120 ± 12 | 140 ± 23 | 155 ± 26 |
PCC35 | 82 ± 11 | 83 ± 8 | 94 ± 10† | 98 ± 10† | 93 ± 13† |
PCC50DIC− | 91 ± 6 | 85 ± 5 | 99 ± 17† | 94 ± 19† | 108 ± 18† |
PCC50DIC+ | 85 ± 9 | 76 ± 4*§ | 133 ± 22‡§ | 132 ± 24‡§ | 165 ± 21‡§ |
MAP, mmHg | |||||
Control | 96 ± 11 | 86 ± 7* | 44 ± 13 | 40 ± 11 | 30 ± 8 |
PCC35 | 94 ± 10 | 87 ± 10* | 56 ± 18 | 66 ± 13† | 65 ± 12† |
PCC50DIC− | 88 ± 9 | 84 ± 5 | 61 ± 9† | 69 ± 9† | 68 ± 5† |
PCC50DIC+ | 87 ± 11 | 78 ± 4§ | 35 ± 10‡§ | 31 ± 14‡§ | 26 ± 13‡§ |
CVP, mmHg | |||||
Control | 7 ± 1 | 7 ± 1 | 4 ± 1 | 3 ± 1 | 2 ± 1 |
PCC35 | 7 ± 2 | 8 ± 1 | 4 ± 1 | 4 ± 2 | 5 ± 1† |
PCC50DIC− | 6 ± 2 | 8 ± 1 | 5 ± 1† | 5 ± 1† | 6 ± 1† |
PCC50DIC+ | 6 ± 1 | 8 ± 1* | 4 ± 1 | 5 ± 1 | 5 ± 1† |
MPAP, mmHg | |||||
Control | 18 ± 2 | 18 ± 2 | 11 ± 3 | 10 ± 2 | 9 ± 2 |
PCC35 | 17 ± 3 | 20 ± 3 | 12 ± 4 | 13 ± 3 | 13 ± 5† |
PCC50DIC− | 17 ± 2 | 18 ± 2* | 15 ± 4 | 15 ± 1† | 16 ± 2† |
PCC50DIC+ | 18 ± 5 | 17 ± 2 | 13 ± 4 | 11 ± 2§ | 11 ± 1§ |
CO, L/min | |||||
Control | 4.2 ± 0.5 | 4.3 ± 0.4 | 3.0 ± 1.2 | 2.4 ± 1.3 | 1.3 ± 0.5 |
PCC35 | 4.3 ± 0.4 | 4.4 ± 0.5 | 3.5 ± 0.4 | 3.3 ± 0.4† | 3.3 ± 0.5† |
PCC50DIC− | 3.9 ± 0.4 | 4.3 ± 0.6 | 3.7 ± 0.7 | 3.7 ± 0.6† | 3.2 ± 0.6† |
PCC50DIC+ | 4.1 ± 0.5 | 3.9 ± 0.2 | 2.6 ± 0.9 | 2.4 ± 0.9 | 1.7 ± 0.2‡§ |