Table 2

Factors retained at the last step in a logistic regression analysis of 2-year survival and achievement of CR

Retained at last stepOdds ratio95% CIP
OS PcG target methylation 0.36 0.19-0.68 .001 
Log (WBC count) 1.2 1.01-1.48 .04 
PFS PcG target methylation 0.47 0.26-0.85 .01 
CR PcG target methylation 0.7 0.22-2.04 .48 
Retained at last stepOdds ratio95% CIP
OS PcG target methylation 0.36 0.19-0.68 .001 
Log (WBC count) 1.2 1.01-1.48 .04 
PFS PcG target methylation 0.47 0.26-0.85 .01 
CR PcG target methylation 0.7 0.22-2.04 .48 

Age at diagnosis (older or younger than 40 years), NPM1 and FLT3ITD mutational status, and log(WBC count) were entered together with PcG methylation levels (high or low, divided at median) at the first step. At each step, all factors with P values > .1 were disregarded.

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