Sample characteristics
| Sample . | Disease stage . | Mutational status . | Karyotype . | FISH analysis . | Available datas . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 17p13 . | 11q23 . | del13q14 . | +12 . | CHIP . | IF . | qPCR . | Teloblot . | ||||
| CLL | |||||||||||
| ALD | A | M | A | N | N | t + del m | N | ✓ | ✓ | ✓ | ✓ |
| ARM | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| BAR | A | UM | ND | del | N | N | N | ✓ | ND | ✓ | ✓ |
| BRI | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| CAR | A | M | ND | N | N | del m | N | ✓ | ND | ✓ | ✓ |
| Dan37 | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| Dan39 | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ND |
| DUR | A | M | ND | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| ECH | A | M | ND | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| FRA | A | UM | ND | N | N | N | N | ✓ | ND | ✓ | ✓ |
| GUI | A | M | N | N | N | N | N | ND | ND | ND | ND |
| IRE | A | UM | A | N | del | del m | N | ✓ | ND | ND | ✓ |
| JOS | A | UM | N | N | del | N | N | ✓ | ✓ | ✓ | ✓ |
| JOU | A | M | ND | N | N | del m + b | N | ND | ✓ | ND | ND |
| LOU | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| LUC | A | M | A (complex) | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| MAR | A | M | ND | N | N | del b | N | ✓ | ✓ | ✓ | ✓ |
| MAR38 | A | M | A (+12) | N | N | N | +12 | ✓ | ✓ | ✓ | ✓ |
| MAR6 | A | M | N | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| PIE | A | M | N | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| RIC | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| SOL | A | UM | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| SUZ | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| Co | |||||||||||
| N120 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N121 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N122 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N123 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N124 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N125 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N126 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N127 | NA | NA | NA | NA | NA | NA | NA | ✓ | ND | ND | ✓ |
| N128 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N129 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N132 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N133 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| Sample . | Disease stage . | Mutational status . | Karyotype . | FISH analysis . | Available datas . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 17p13 . | 11q23 . | del13q14 . | +12 . | CHIP . | IF . | qPCR . | Teloblot . | ||||
| CLL | |||||||||||
| ALD | A | M | A | N | N | t + del m | N | ✓ | ✓ | ✓ | ✓ |
| ARM | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| BAR | A | UM | ND | del | N | N | N | ✓ | ND | ✓ | ✓ |
| BRI | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| CAR | A | M | ND | N | N | del m | N | ✓ | ND | ✓ | ✓ |
| Dan37 | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| Dan39 | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ND |
| DUR | A | M | ND | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| ECH | A | M | ND | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| FRA | A | UM | ND | N | N | N | N | ✓ | ND | ✓ | ✓ |
| GUI | A | M | N | N | N | N | N | ND | ND | ND | ND |
| IRE | A | UM | A | N | del | del m | N | ✓ | ND | ND | ✓ |
| JOS | A | UM | N | N | del | N | N | ✓ | ✓ | ✓ | ✓ |
| JOU | A | M | ND | N | N | del m + b | N | ND | ✓ | ND | ND |
| LOU | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| LUC | A | M | A (complex) | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| MAR | A | M | ND | N | N | del b | N | ✓ | ✓ | ✓ | ✓ |
| MAR38 | A | M | A (+12) | N | N | N | +12 | ✓ | ✓ | ✓ | ✓ |
| MAR6 | A | M | N | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| PIE | A | M | N | N | N | del m + b | N | ✓ | ✓ | ✓ | ✓ |
| RIC | A | M | N | N | N | N | N | ✓ | ✓ | ✓ | ✓ |
| SOL | A | UM | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| SUZ | A | M | N | N | N | del m | N | ✓ | ✓ | ✓ | ✓ |
| Co | |||||||||||
| N120 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N121 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N122 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N123 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N124 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N125 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N126 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N127 | NA | NA | NA | NA | NA | NA | NA | ✓ | ND | ND | ✓ |
| N128 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N129 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
| N132 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ✓ | ✓ |
| N133 | NA | NA | NA | NA | NA | NA | NA | ✓ | ✓ | ND | ✓ |
NA indicates nonapplicable; ND, not done; M, mutated; UM, unmutated; A, abnormal; N, normal; del, deletion; m, monoallelic; b, biallelic; del, deletion; +12, trisomy 12; and t, translocation.