Mismatched related HSCT for SCD
| Reference . | Transplant regimen . | Number of patients (age, y) . | Alive without SCD . | Acute GVHD . | Chronic GVHD . | Death (cause) . | Comments . |
|---|---|---|---|---|---|---|---|
| Raj et al, 200484 | Flu 90 mg/m2, 200 cGy TBI, CSA + MMF | 1 (14 y) | 0 | 0 | 0 | Not available | Graft failure |
| Brodsky et al, 200885 | Cy 29 mg/kg, Flu 150 mg/m2, 200 cGy TBI, Cy 100 mg/kg, tac + MMF | 1 (33) | 1 | 0 | 0 | N/A | Pt with concomitant PNH |
| Reference . | Transplant regimen . | Number of patients (age, y) . | Alive without SCD . | Acute GVHD . | Chronic GVHD . | Death (cause) . | Comments . |
|---|---|---|---|---|---|---|---|
| Raj et al, 200484 | Flu 90 mg/m2, 200 cGy TBI, CSA + MMF | 1 (14 y) | 0 | 0 | 0 | Not available | Graft failure |
| Brodsky et al, 200885 | Cy 29 mg/kg, Flu 150 mg/m2, 200 cGy TBI, Cy 100 mg/kg, tac + MMF | 1 (33) | 1 | 0 | 0 | N/A | Pt with concomitant PNH |
cGy, centi-Gray; CSA, cyclosporine A; Cy, cyclophosphamide; Flu, fludarabine; MMF, mycophenolate mofetil; N/A, not applicable; PNH, paroxysmal nocturnal hemoglobinuria; SCD, sickle cell disease; tac, tacrolimus; and TBI, total body irradiation.