Table 1
At diagnosis 
    Only in AP/BC patients 
During first-line imatinib therapy 
    In case of failure 
    In case of an increase in BCR-ABL transcript levels leading to MMR loss 
    In any other case of suboptimal response 
During second-line dasatinib or nilotinib therapy 
    In case of hematologic or cytogenetic failure 
At diagnosis 
    Only in AP/BC patients 
During first-line imatinib therapy 
    In case of failure 
    In case of an increase in BCR-ABL transcript levels leading to MMR loss 
    In any other case of suboptimal response 
During second-line dasatinib or nilotinib therapy 
    In case of hematologic or cytogenetic failure 

AP indicates accelerated phase.

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