Table 2

Frequency of BCR-ABL+ cells on limiting dilution and FISH analysis

PatientYears on IM treatmentFrequency of BCR-ABL+ cells, %
Limiting dilution analysis
FISH
CD34+CD38+CD34+CD38CD34+CD38*CD34+CD38+*
476 0.03 0.20   
 4.5 0.05 0.09   
 5.5 0.25 0.54 0 (200)  
469 0.16 0.81   
 0.12 0.34   
397 0.32 1.06 0 (50) 0 (233) 
 0.15 0.47 0 (200) 0 (206) 
 6.5 0.21 0.41 1 (200) 0 (216) 
273 4.5 0.27 1.61 0.5 (200) 0 (246) 
 6.5 0.17 0.56 1 (98) 0 (220) 
296 0.23 0.46   
 0.04 0.75   
299 0.29 0.47   
 0.32 0.45   
PatientYears on IM treatmentFrequency of BCR-ABL+ cells, %
Limiting dilution analysis
FISH
CD34+CD38+CD34+CD38CD34+CD38*CD34+CD38+*
476 0.03 0.20   
 4.5 0.05 0.09   
 5.5 0.25 0.54 0 (200)  
469 0.16 0.81   
 0.12 0.34   
397 0.32 1.06 0 (50) 0 (233) 
 0.15 0.47 0 (200) 0 (206) 
 6.5 0.21 0.41 1 (200) 0 (216) 
273 4.5 0.27 1.61 0.5 (200) 0 (246) 
 6.5 0.17 0.56 1 (98) 0 (220) 
296 0.23 0.46   
 0.04 0.75   
299 0.29 0.47   
 0.32 0.45   
*

Numbers in parentheses represent number of cells analyzed.

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