Table 1

Patient characteristics

Number of study patients 71 
Median age, y (range) 8.0 (0.6-23.1) 
Median follow-up after transplantation, y (range) 1.5 (0.1-4.3) 
Disease status xabefore transplantation, n 
    CR1 23 
    CR2 29 
    CR > 2 
    NR 17 
Donor, n 
    MSD 23 
    MUD 31 
    MMFD 17 
Stem-cell source, n 
    BM 45 
    PB 23 
    Other 
T-cell depletion, n 
    Yes 15 
    No 56 
Myeloablative conditioning regimen, n 
    Busulfan-based  
        Bus + Cyc + Mel ± ATG, n 34 
        Bus + Cyc ± ATG 
    Other (TBI/treosulfan-based) 
RIC, n 
    Flu + Thio + Mel + OKT3 12 
    TBI (4 Gy) + Amsa + Flu + Cyt ± Cyc ± Bus ± ATG 
    Other 
Number of study patients 71 
Median age, y (range) 8.0 (0.6-23.1) 
Median follow-up after transplantation, y (range) 1.5 (0.1-4.3) 
Disease status xabefore transplantation, n 
    CR1 23 
    CR2 29 
    CR > 2 
    NR 17 
Donor, n 
    MSD 23 
    MUD 31 
    MMFD 17 
Stem-cell source, n 
    BM 45 
    PB 23 
    Other 
T-cell depletion, n 
    Yes 15 
    No 56 
Myeloablative conditioning regimen, n 
    Busulfan-based  
        Bus + Cyc + Mel ± ATG, n 34 
        Bus + Cyc ± ATG 
    Other (TBI/treosulfan-based) 
RIC, n 
    Flu + Thio + Mel + OKT3 12 
    TBI (4 Gy) + Amsa + Flu + Cyt ± Cyc ± Bus ± ATG 
    Other 

Amsa indicates amsacrine; ATG, antithymocyte globulin; Bus, busulfan; Cyc, cyclophosphamide; Cyt, cytarabine; Flu, fludarabine; OKT3, anti-CD3 mAb; Mel, melphalan; TBI, total body irradiation; and Thio, thiotepa.

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