Table 1

Characteristics of the mouse cohorts

DonorPopulationTreatmentRecipientHematopoietic tumors
%B-cellT-cell
AR       
    n = 19 — — — 26 5/19 0/19 
    n = 11 Sca1+ Mock WT 100 10/11 1/11 
    n = 12 Sca1+ GFP WT 100 10/12 2/12 
    n = 10 Sca1+CD19 GFP WT 60 4/10 2/10 
    n = 8 Sca1+CD19 Rag1 WT 88 2/8 5/8 
A       
    n = 17 — — — 17 0/17 3/17 
    n = 9 Sca1+ Mock WT 11 0/9 1/9 
    n = 9 Sca1+ GFP WT 22 0/9 2/9 
DonorPopulationTreatmentRecipientHematopoietic tumors
%B-cellT-cell
AR       
    n = 19 — — — 26 5/19 0/19 
    n = 11 Sca1+ Mock WT 100 10/11 1/11 
    n = 12 Sca1+ GFP WT 100 10/12 2/12 
    n = 10 Sca1+CD19 GFP WT 60 4/10 2/10 
    n = 8 Sca1+CD19 Rag1 WT 88 2/8 5/8 
A       
    n = 17 — — — 17 0/17 3/17 
    n = 9 Sca1+ Mock WT 11 0/9 1/9 
    n = 9 Sca1+ GFP WT 22 0/9 2/9 

Numbers of mice are indicated for each group used in this study, along with the donor population, ex vivo treatments, the percentage of animals having developed hematopoietic tumors, and the tumor phenotype.

AR indicates p19Arf−/−Rag1−/−; A, p19Arf−/−; —, not applicable; WT, wild type; and GFP, green fluorescent protein.

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