Characteristics of the mouse cohorts
Donor . | Population . | Treatment . | Recipient . | Hematopoietic tumors . | ||
---|---|---|---|---|---|---|
% . | B-cell . | T-cell . | ||||
AR | ||||||
n = 19 | — | — | — | 26 | 5/19 | 0/19 |
n = 11 | Sca1+ | Mock | WT | 100 | 10/11 | 1/11 |
n = 12 | Sca1+ | GFP | WT | 100 | 10/12 | 2/12 |
n = 10 | Sca1+CD19− | GFP | WT | 60 | 4/10 | 2/10 |
n = 8 | Sca1+CD19− | Rag1 | WT | 88 | 2/8 | 5/8 |
A | ||||||
n = 17 | — | — | — | 17 | 0/17 | 3/17 |
n = 9 | Sca1+ | Mock | WT | 11 | 0/9 | 1/9 |
n = 9 | Sca1+ | GFP | WT | 22 | 0/9 | 2/9 |
Donor . | Population . | Treatment . | Recipient . | Hematopoietic tumors . | ||
---|---|---|---|---|---|---|
% . | B-cell . | T-cell . | ||||
AR | ||||||
n = 19 | — | — | — | 26 | 5/19 | 0/19 |
n = 11 | Sca1+ | Mock | WT | 100 | 10/11 | 1/11 |
n = 12 | Sca1+ | GFP | WT | 100 | 10/12 | 2/12 |
n = 10 | Sca1+CD19− | GFP | WT | 60 | 4/10 | 2/10 |
n = 8 | Sca1+CD19− | Rag1 | WT | 88 | 2/8 | 5/8 |
A | ||||||
n = 17 | — | — | — | 17 | 0/17 | 3/17 |
n = 9 | Sca1+ | Mock | WT | 11 | 0/9 | 1/9 |
n = 9 | Sca1+ | GFP | WT | 22 | 0/9 | 2/9 |
Numbers of mice are indicated for each group used in this study, along with the donor population, ex vivo treatments, the percentage of animals having developed hematopoietic tumors, and the tumor phenotype.
AR indicates p19Arf−/−Rag1−/−; A, p19Arf−/−; —, not applicable; WT, wild type; and GFP, green fluorescent protein.