Impacts of clinicopathologic features on relapse in 76 APL patients on oral As2O3 maintenance
| Clinicopathologic parameters . | Outcome . | P . | |
|---|---|---|---|
| Remission . | Relapse . | ||
| Sex | |||
| Male | 28 | 7 | |
| Female | 40 | 1 | .02 |
| Age, y | |||
| ≤ 40 | 24 | 2 | |
| > 40 | 44 | 6 | NS (.70) |
| Presentation WBC count | |||
| ≤ 10 × 109/L | 60 | 6 | |
| > 10 × 109/L | 8 | 2 | NS (.28) |
| Presentation platelet count | |||
| < 40 × 109/L | 46 | 5 | |
| ≥ 40 × 109/L | 22 | 3 | NS (1.0) |
| APL differentiation syndrome | |||
| Present | 13 | 3 | |
| Absent | 55 | 5 | NS (.35) |
| Peak WBC count | |||
| ≤ 10 × 109/L | 28 | 3 | |
| > 10 × 109/L | 30 | 5 | NS (.46) |
| Maintenance regimens | |||
| A | 17 | 3 | |
| AA | 16 | 3 | |
| AAA | 35 | 2 | NS (.37) |
| Second cancers (before/after maintenance) | |||
| Present | 13 | 1 | |
| Absent | 35 | 7 | NS (1.0) |
| Clinicopathologic parameters . | Outcome . | P . | |
|---|---|---|---|
| Remission . | Relapse . | ||
| Sex | |||
| Male | 28 | 7 | |
| Female | 40 | 1 | .02 |
| Age, y | |||
| ≤ 40 | 24 | 2 | |
| > 40 | 44 | 6 | NS (.70) |
| Presentation WBC count | |||
| ≤ 10 × 109/L | 60 | 6 | |
| > 10 × 109/L | 8 | 2 | NS (.28) |
| Presentation platelet count | |||
| < 40 × 109/L | 46 | 5 | |
| ≥ 40 × 109/L | 22 | 3 | NS (1.0) |
| APL differentiation syndrome | |||
| Present | 13 | 3 | |
| Absent | 55 | 5 | NS (.35) |
| Peak WBC count | |||
| ≤ 10 × 109/L | 28 | 3 | |
| > 10 × 109/L | 30 | 5 | NS (.46) |
| Maintenance regimens | |||
| A | 17 | 3 | |
| AA | 16 | 3 | |
| AAA | 35 | 2 | NS (.37) |
| Second cancers (before/after maintenance) | |||
| Present | 13 | 1 | |
| Absent | 35 | 7 | NS (1.0) |