Table 1 Summary of the 2 statistical... | American Society of Hematology

Table 1

Summary of the 2 statistical models for the imatinib response data

	Biphasic exponential model	Exponential model
Short-term (12 mo) mesylate imatinib response patient cohort (n = 51)
Minimum* of R_i²	0.91	0
First quartile* of R_i²	0.98	0.76
Median* of R_i²	0.99	0.83
Mean* of R_i²	0.98	0.79
Third quartile* of R_i²	0.99	0.87
Maximum* of R_i²	1	0.96
†Final R²	0.98	0.81
‡Sum of BICs	−62.6	28.0
Long-term (10 y) imatinib response patient cohort (n = 22)
Minimum* of R_i²	0.67	0.62
First quartile* of R_i²	0.85	0.69
Median* of R_i²	0.88	0.77
Mean* of R_i²	0.87	0.77
Third quartile* of R_i²	0.91	0.84
Maximum* of R_i²	0.96	0.93
†Final R²	0.89	0.80
‡Sum of BICs	−23.3	−15.3

	Biphasic exponential model	Exponential model
Short-term (12 mo) mesylate imatinib response patient cohort (n = 51)
Minimum* of R_i²	0.91	0
First quartile* of R_i²	0.98	0.76
Median* of R_i²	0.99	0.83
Mean* of R_i²	0.98	0.79
Third quartile* of R_i²	0.99	0.87
Maximum* of R_i²	1	0.96
†Final R²	0.98	0.81
‡Sum of BICs	−62.6	28.0
Long-term (10 y) imatinib response patient cohort (n = 22)
Minimum* of R_i²	0.67	0.62
First quartile* of R_i²	0.85	0.69
Median* of R_i²	0.88	0.77
Mean* of R_i²	0.87	0.77
Third quartile* of R_i²	0.91	0.84
Maximum* of R_i²	0.96	0.93
†Final R²	0.89	0.80
‡Sum of BICs	−23.3	−15.3

i = 1, …, N, calculated from the corresponding fitted model for each patient, where N is the total number of patients and R_i² = 1 − SSE_i/SST_i.

†

Final R², calculated as 1 − Σ_i SSE_i/Σ_i SST_i, evaluates the overall fit of the corresponding model to the whole time series data with all patients.

‡

Sum of BICs is the sum of BICs over all subjects for each model.

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