Observed and expected cancers and SIRs among patients Danish patients diagnosed with CML during 1977-2008 and followed for new primary cancers
| . | Person-years of CML patients . | CML patients with nonhematologic cancers, n . | Nonhematologic cancers expected, n . | SIR (95% CI) . | CML patients with hematologic cancers, n . | Hematologic cancers expected, n . | SIR (95% CI) . |
|---|---|---|---|---|---|---|---|
| All | 3960 | 75 | 46.0 | 1.6 (1.3-2.0) | 14 | 2.7 | 5.2 (2.8-8.7) |
| Women | 1788 | 27 | 21.4 | 1.3 (0.8-1.8) | 5 | 1.1 | 4.7 (1.5-11.0) |
| Men | 2172 | 48 | 24.5 | 2.0 (1.4-2.6) | 9 | 1.6 | 5.5 (2.5-10.4) |
| Age at CML diagnosis, y | |||||||
| 20-49 | 1772 | 20 | 7.6 | 2.6 (1.6-4.1) | 2 | 0.4 | 5.3 (0.6-19.0) |
| 50-69 | 1563 | 38 | 22.5 | 1.7 (1.2-2.3) | 2 | 1.3 | 1.5 (0.2-5.5) |
| 70+ | 625 | 17 | 15.9 | 1.1 (0.6-1.7) | 10 | 1.0 | 9.9 (4.7-18.1) |
| Year of CML diagnosis | |||||||
| 1977-1994 | 2250 | 39 | 23.8 | 1.6 (1.2-2.2) | 10 | 1.4 | 7.2 (3.5-13.3) |
| 1995-2008 | 1710 | 36 | 22.2 | 1.6 (1.1-2.3) | 4 | 1.3 | 3.1 (0.8-7.0) |
| Follow-up time | |||||||
| Year 2 | 896 | 14 | 11.0 | 1.3 (0.7-2.1) | 6 | 0.7 | 9.2 (3.3-20.0) |
| Years 3-5 | 1561 | 27 | 18.8 | 1.4 (1.0-2.1) | 5 | 1.1 | 4.5 (1.5-10.5) |
| Years 6+ | 1503 | 34 | 16.2 | 2.1 (1.5-2.9) | 3 | 0.9 | 3.2 (0.7-9.3) |
| Hospital contact type (from 1995 on) | |||||||
| Outpatient only | 1109 | 15 | 8.6 | 1.7 (1.0-2.9) | 0 | 0.5 | |
| Inpatient admission | 601 | 21 | 13.5 | 1.6 (1.0-2.4) | 4 | 0.8 | 5.0 (1.4-12.9) |
| . | Person-years of CML patients . | CML patients with nonhematologic cancers, n . | Nonhematologic cancers expected, n . | SIR (95% CI) . | CML patients with hematologic cancers, n . | Hematologic cancers expected, n . | SIR (95% CI) . |
|---|---|---|---|---|---|---|---|
| All | 3960 | 75 | 46.0 | 1.6 (1.3-2.0) | 14 | 2.7 | 5.2 (2.8-8.7) |
| Women | 1788 | 27 | 21.4 | 1.3 (0.8-1.8) | 5 | 1.1 | 4.7 (1.5-11.0) |
| Men | 2172 | 48 | 24.5 | 2.0 (1.4-2.6) | 9 | 1.6 | 5.5 (2.5-10.4) |
| Age at CML diagnosis, y | |||||||
| 20-49 | 1772 | 20 | 7.6 | 2.6 (1.6-4.1) | 2 | 0.4 | 5.3 (0.6-19.0) |
| 50-69 | 1563 | 38 | 22.5 | 1.7 (1.2-2.3) | 2 | 1.3 | 1.5 (0.2-5.5) |
| 70+ | 625 | 17 | 15.9 | 1.1 (0.6-1.7) | 10 | 1.0 | 9.9 (4.7-18.1) |
| Year of CML diagnosis | |||||||
| 1977-1994 | 2250 | 39 | 23.8 | 1.6 (1.2-2.2) | 10 | 1.4 | 7.2 (3.5-13.3) |
| 1995-2008 | 1710 | 36 | 22.2 | 1.6 (1.1-2.3) | 4 | 1.3 | 3.1 (0.8-7.0) |
| Follow-up time | |||||||
| Year 2 | 896 | 14 | 11.0 | 1.3 (0.7-2.1) | 6 | 0.7 | 9.2 (3.3-20.0) |
| Years 3-5 | 1561 | 27 | 18.8 | 1.4 (1.0-2.1) | 5 | 1.1 | 4.5 (1.5-10.5) |
| Years 6+ | 1503 | 34 | 16.2 | 2.1 (1.5-2.9) | 3 | 0.9 | 3.2 (0.7-9.3) |
| Hospital contact type (from 1995 on) | |||||||
| Outpatient only | 1109 | 15 | 8.6 | 1.7 (1.0-2.9) | 0 | 0.5 | |
| Inpatient admission | 601 | 21 | 13.5 | 1.6 (1.0-2.4) | 4 | 0.8 | 5.0 (1.4-12.9) |