Hematological and iron parameters in ID and IR mice before and after injection of LPS
| . | IR . | IR + LPS . | ID . | ID + LPS . |
|---|---|---|---|---|
| RBC, ×1012/L | 9.2 ± 0.83 | 8.9 ± 0.57 | 7.9 ± 0.84* | 7.1 ± 1.15 |
| Hgb, g/L | 140 ± 9.1 | 142 ± 10 | 106 ± 12* | 100 ± 15 |
| Hct, % | 46.44 ± 4.92 | 44.12 ± 3.11 | 35.34 ± 5.09* | 32.0 ± 4.42 |
| MCV, ×10−15/L | 50.42 ± 1.04 | 49.57 ± 0.62 | 44.55 ± 2.10* | 43.04 ± 1.52 |
| MCH, pg | 15.25 ± 0.73 | 16.01 ± 0.89 | 13.46 ± 0.66* | 13.52 ± 1.23 |
| WBC, ×109/L | 7.38 ± 1.26 | 3.54 ± 1.31† | 11.7 ± 2.59* | 4.67 ± 2.1† |
| TS, % | 58.08 ± 5.97 | 43.98 ± 5.18‡ | 23.3 ± 8.91‡ | 25.56 ± 4.61 |
| LIC, μg iron/g liver | 134.9 ± 3.09 | 248.9 ± 21.48§ | 101.8 ± 5.78‡ | 119.8 ± 5.51 |
| . | IR . | IR + LPS . | ID . | ID + LPS . |
|---|---|---|---|---|
| RBC, ×1012/L | 9.2 ± 0.83 | 8.9 ± 0.57 | 7.9 ± 0.84* | 7.1 ± 1.15 |
| Hgb, g/L | 140 ± 9.1 | 142 ± 10 | 106 ± 12* | 100 ± 15 |
| Hct, % | 46.44 ± 4.92 | 44.12 ± 3.11 | 35.34 ± 5.09* | 32.0 ± 4.42 |
| MCV, ×10−15/L | 50.42 ± 1.04 | 49.57 ± 0.62 | 44.55 ± 2.10* | 43.04 ± 1.52 |
| MCH, pg | 15.25 ± 0.73 | 16.01 ± 0.89 | 13.46 ± 0.66* | 13.52 ± 1.23 |
| WBC, ×109/L | 7.38 ± 1.26 | 3.54 ± 1.31† | 11.7 ± 2.59* | 4.67 ± 2.1† |
| TS, % | 58.08 ± 5.97 | 43.98 ± 5.18‡ | 23.3 ± 8.91‡ | 25.56 ± 4.61 |
| LIC, μg iron/g liver | 134.9 ± 3.09 | 248.9 ± 21.48§ | 101.8 ± 5.78‡ | 119.8 ± 5.51 |
Mean hematological and iron parameters in ID and IR mice.
ID indicates iron deficient; IR, iron replete; LPS, lipopolysaccharide; Hgb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; WBC, white blood cell; TS, transferrin saturation; and LIC, liver iron concentration.
P < .0005 (vs IR mice).
P < .0005 (LPS-treated vs untreated mice).
P < .05 (vs IR mice).
P < .05 (vs IR mice).