RRs with 95% CIs for associations of sun sensitivity or sun exposure with risk of overall NHL, diffuse large B-cell lymphoma, and follicular lymphoma
| Sun sensitivity or exposure . | Overall non-Hodgkin lymphoma . | Diffuse large B-cell lymphoma . | Follicular lymphoma . | |||
|---|---|---|---|---|---|---|
| Cases (n) . | RR (95% CI)* . | Cases (n) . | RR (95% CI)* . | Cases (n) . | RR (95% CI)* . | |
| Skin reaction to hot sun exposure for 1 hour without protection | ||||||
| Severe burn with blistering | 93 | 1.00 (reference) | 27 | 1.00 (reference) | 23 | 1.00 (reference) |
| Severe burn without blistering | 124 | 0.97 (0.74-1.27) | 36 | 0.97 (0.59-1.60) | 21 | 0.64 (0.35-1.16) |
| Mild burn, then tan or darken | 271 | 0.95 (0.75-1.20) | 60 | 0.72 (0.46-1.13) | 56 | 0.77 (0.48-1.26) |
| No burn | 128 | 0.95 (0.72-1.24) | 30 | 0.74 (0.44-1.25) | 19 | 0.59 (0.32-1.08) |
| Skin reaction to repeated sun exposure | ||||||
| Deep tan or darkening | 136 | 1.00 (reference) | 33 | 1.00 (reference) | 27 | 1.00 (reference) |
| Moderate tan or darkening | 280 | 0.99 (0.81-1.22) | 69 | 1.01 (0.66-1.52) | 53 | 0.97 (0.61-1.54) |
| Light or no tan or darkening | 191 | 0.90 (0.72-1.12) | 51 | 0.99 (0.64-1.54) | 37 | 0.91 (0.56-1.50) |
| Age at first blistering sunburn, y | ||||||
| Never | 193 | 1.00 (reference) | 56 | 1.00 (reference) | 29 | 1.00 (reference) |
| ≤ 10 | 82 | 0.96 (0.74-1.24) | 22 | 0.91 (0.55-1.49) | 18 | 1.36 (0.75-2.45) |
| 11-15 | 154 | 1.21 (0.98-1.49) | 37 | 1.01 (0.67-1.54) | 31 | 1.56 (0.94-2.60) |
| 16-20 | 119 | 1.15 (0.91-1.44) | 24 | 0.80 (0.49-1.29) | 23 | 1.46 (0.85-2.53) |
| ≥ 21 | 63 | 1.03 (0.77-1.37) | 14 | 0.79 (0.44-1.42) | 16 | 1.78 (0.97-3.28) |
| Number of times with blistering sunburn | ||||||
| Never | 193 | 1.00 (reference) | 56 | 1.00 (reference) | 29 | 1.00 (reference) |
| 1-2 | 182 | 1.08 (0.88-1.32) | 44 | 0.90 (0.61-1.34) | 36 | 1.43 (0.88-2.34) |
| 3-4 | 127 | 1.20 (0.96-1.51) | 26 | 0.86 (0.54-1.36) | 31 | 1.91 (1.15-3.18) |
| ≥ 5 | 100 | 1.03 (0.81-1.32) | 23 | 0.83 (0.51-1.35) | 21 | 1.38 (0.78-2.43) |
| History of melanoma or other skin cancer | ||||||
| No | 528 | 1.00 (reference) | 138 | 1.00 (reference) | 99 | 1.00 (reference) |
| Yes | 101 | 1.11 (0.89-1.37) | 17 | 0.70 (0.42-1.16) | 23 | 1.49 (0.94-2.37) |
| Sun sensitivity or exposure . | Overall non-Hodgkin lymphoma . | Diffuse large B-cell lymphoma . | Follicular lymphoma . | |||
|---|---|---|---|---|---|---|
| Cases (n) . | RR (95% CI)* . | Cases (n) . | RR (95% CI)* . | Cases (n) . | RR (95% CI)* . | |
| Skin reaction to hot sun exposure for 1 hour without protection | ||||||
| Severe burn with blistering | 93 | 1.00 (reference) | 27 | 1.00 (reference) | 23 | 1.00 (reference) |
| Severe burn without blistering | 124 | 0.97 (0.74-1.27) | 36 | 0.97 (0.59-1.60) | 21 | 0.64 (0.35-1.16) |
| Mild burn, then tan or darken | 271 | 0.95 (0.75-1.20) | 60 | 0.72 (0.46-1.13) | 56 | 0.77 (0.48-1.26) |
| No burn | 128 | 0.95 (0.72-1.24) | 30 | 0.74 (0.44-1.25) | 19 | 0.59 (0.32-1.08) |
| Skin reaction to repeated sun exposure | ||||||
| Deep tan or darkening | 136 | 1.00 (reference) | 33 | 1.00 (reference) | 27 | 1.00 (reference) |
| Moderate tan or darkening | 280 | 0.99 (0.81-1.22) | 69 | 1.01 (0.66-1.52) | 53 | 0.97 (0.61-1.54) |
| Light or no tan or darkening | 191 | 0.90 (0.72-1.12) | 51 | 0.99 (0.64-1.54) | 37 | 0.91 (0.56-1.50) |
| Age at first blistering sunburn, y | ||||||
| Never | 193 | 1.00 (reference) | 56 | 1.00 (reference) | 29 | 1.00 (reference) |
| ≤ 10 | 82 | 0.96 (0.74-1.24) | 22 | 0.91 (0.55-1.49) | 18 | 1.36 (0.75-2.45) |
| 11-15 | 154 | 1.21 (0.98-1.49) | 37 | 1.01 (0.67-1.54) | 31 | 1.56 (0.94-2.60) |
| 16-20 | 119 | 1.15 (0.91-1.44) | 24 | 0.80 (0.49-1.29) | 23 | 1.46 (0.85-2.53) |
| ≥ 21 | 63 | 1.03 (0.77-1.37) | 14 | 0.79 (0.44-1.42) | 16 | 1.78 (0.97-3.28) |
| Number of times with blistering sunburn | ||||||
| Never | 193 | 1.00 (reference) | 56 | 1.00 (reference) | 29 | 1.00 (reference) |
| 1-2 | 182 | 1.08 (0.88-1.32) | 44 | 0.90 (0.61-1.34) | 36 | 1.43 (0.88-2.34) |
| 3-4 | 127 | 1.20 (0.96-1.51) | 26 | 0.86 (0.54-1.36) | 31 | 1.91 (1.15-3.18) |
| ≥ 5 | 100 | 1.03 (0.81-1.32) | 23 | 0.83 (0.51-1.35) | 21 | 1.38 (0.78-2.43) |
| History of melanoma or other skin cancer | ||||||
| No | 528 | 1.00 (reference) | 138 | 1.00 (reference) | 99 | 1.00 (reference) |
| Yes | 101 | 1.11 (0.89-1.37) | 17 | 0.70 (0.42-1.16) | 23 | 1.49 (0.94-2.37) |
All models adjusted for age (as timescale) and calendar-year effects.