Table 3 Univariate analysis: FN BMD... | American Society of Hematology

Table 3

Univariate analysis: FN BMD results

	All patients		Chemotherapy group		HSCT group
	Mean Z-score ± SEM	Univariable P	Mean Z-score ± SEM	Univariable P	Mean Z-score ± SEM	Univariable P
Patient and disease characteristics
Sex
Female	−0.34 ± 0.10	.07	−0.13 ± 0.12	.28	−0.87 ± 0.14	.03
Male	−0.03 ± 0.13		0.08 ± 0.16		−0.22 ± 0.23
Initial diagnosis
ALL	−0.15 ± 0.09	.33	−0.02 ± 0.10	.71	−0.53 ± 0.19	.78
AML	−0.36 ± 0.19		−0.18 ± 0.31		−0.44 ± 0.25
Age at diagnosis	NA	.53	NA	.04	NA	.09
Age at HSCT					NA	.09
Follow-up	NA	.46	NA	.30	NA	.79
Treatment modalities
Corticotherapy
No	−0.39 ± 0.15	.33	−0.18 ± 0.31	.66	−0.54 ± 0.15	.87
Yes	−0.16 ± 0.09		−0.02 ± 0.10		−0.48 ± 0.20
Dexamethasone
No	−0.21 ± 0.13	.87	−0.01 ± 0.15	.88	−0.43 ± 0.22	.66
Yes	−0.18 ± 0.11		−0.05 ± 0.13		−0.57 ± 0.19
HSCT
No	−0.04 ± 0.10	.009
Yes	−0.49 ± 0.15
TBI
No					−0.53 ± 0.18	.87
Yes					−0.48 ± 0.20
Type of graft
Allograft					−0.41 ± 0.21	.43
Autograft					−0.66 ± 0.20
Posttransplantation steroid therapy
No					−0.55 ± 0.14	.69
Yes					−0.41 ± 0.32
Transplantation-related complications
Significant GVHD*
No					−0.37 ± 0.18	.22
Yes					−0.78 ± 0.25
Hypogonadism
No					−0.10 ± 0.23
Compensated					−0.59 ± 0.18	.004
Uncompensated					−1.37 ± 0.26
GHD
No					−0.45 ± 0.16	.27
Yes					−1.08 ± 0.42

	All patients		Chemotherapy group		HSCT group
	Mean Z-score ± SEM	Univariable P	Mean Z-score ± SEM	Univariable P	Mean Z-score ± SEM	Univariable P
Patient and disease characteristics
Sex
Female	−0.34 ± 0.10	.07	−0.13 ± 0.12	.28	−0.87 ± 0.14	.03
Male	−0.03 ± 0.13		0.08 ± 0.16		−0.22 ± 0.23
Initial diagnosis
ALL	−0.15 ± 0.09	.33	−0.02 ± 0.10	.71	−0.53 ± 0.19	.78
AML	−0.36 ± 0.19		−0.18 ± 0.31		−0.44 ± 0.25
Age at diagnosis	NA	.53	NA	.04	NA	.09
Age at HSCT					NA	.09
Follow-up	NA	.46	NA	.30	NA	.79
Treatment modalities
Corticotherapy
No	−0.39 ± 0.15	.33	−0.18 ± 0.31	.66	−0.54 ± 0.15	.87
Yes	−0.16 ± 0.09		−0.02 ± 0.10		−0.48 ± 0.20
Dexamethasone
No	−0.21 ± 0.13	.87	−0.01 ± 0.15	.88	−0.43 ± 0.22	.66
Yes	−0.18 ± 0.11		−0.05 ± 0.13		−0.57 ± 0.19
HSCT
No	−0.04 ± 0.10	.009
Yes	−0.49 ± 0.15
TBI
No					−0.53 ± 0.18	.87
Yes					−0.48 ± 0.20
Type of graft
Allograft					−0.41 ± 0.21	.43
Autograft					−0.66 ± 0.20
Posttransplantation steroid therapy
No					−0.55 ± 0.14	.69
Yes					−0.41 ± 0.32
Transplantation-related complications
Significant GVHD*
No					−0.37 ± 0.18	.22
Yes					−0.78 ± 0.25
Hypogonadism
No					−0.10 ± 0.23
Compensated					−0.59 ± 0.18	.004
Uncompensated					−1.37 ± 0.26
GHD
No					−0.45 ± 0.16	.27
Yes					−1.08 ± 0.42

Significant GVHD indicates acute GVHD grades II, III, or IV or chronic extensive GVHD.