NLPHL and HL samples used in NPAT sequencing
| Description of patients . | No. of cases available . | Deletion of c. 2437-2438delAG . | Deletion of serine 724 . |
|---|---|---|---|
| Finland | |||
| Finnish NLPHL family | 4 | 4 | 0 |
| HL patients from other Finnish NLPHL families | 27 | 0 | 0 |
| NLPHL patients with early-onset disease (< 30 years) | 38 | 0 | 1 |
| NLPHL patients from same geographic region as the original family | 8 | 0 | 0 |
| Healthy controls | 282 | 0 | 2 |
| United Kingdom | |||
| HL patients with a family history of a lymphoproliferative disorder | 26 | 0 | 2 |
| Sporadic HL patients | 67 | 0 | 4 |
| Healthy controls | 177 | 0 | 3 |
| Previously reported NLPHL cases | |||
| United Kingdom/India: 2 siblings with NLPHL | 2 | 0 | 0 |
| France: a family of 3 NLPHL patients | 3 | 0 | 0 |
| Turkey: mother and son with NLPHL | 2 | 0 | 0 |
| DEV cell line | 1 | 0 | 0 |
| Description of patients . | No. of cases available . | Deletion of c. 2437-2438delAG . | Deletion of serine 724 . |
|---|---|---|---|
| Finland | |||
| Finnish NLPHL family | 4 | 4 | 0 |
| HL patients from other Finnish NLPHL families | 27 | 0 | 0 |
| NLPHL patients with early-onset disease (< 30 years) | 38 | 0 | 1 |
| NLPHL patients from same geographic region as the original family | 8 | 0 | 0 |
| Healthy controls | 282 | 0 | 2 |
| United Kingdom | |||
| HL patients with a family history of a lymphoproliferative disorder | 26 | 0 | 2 |
| Sporadic HL patients | 67 | 0 | 4 |
| Healthy controls | 177 | 0 | 3 |
| Previously reported NLPHL cases | |||
| United Kingdom/India: 2 siblings with NLPHL | 2 | 0 | 0 |
| France: a family of 3 NLPHL patients | 3 | 0 | 0 |
| Turkey: mother and son with NLPHL | 2 | 0 | 0 |
| DEV cell line | 1 | 0 | 0 |
The number of cases with a deletion in NPAT is shown.