Table 4

Variables having an independent association with log hepcidin concentration by multiple linear regression

Beta (95% CI)P
All subjects (n=126)*   
    VHLR200W homozygosity −0.52 (−0.74 to −0.30) < .0001 
    Serum ferritin (log) 0.43 (0.27-0.58) < .0001 
    Serum erythropoietin (log) −0.06 (−0.30-0.18) .6 
Subjects with ferritin ≤ 25 μg/L (n = 71)   
    VHLR200W homozygosity −0.42 (−0.72 to −0.13) .006 
    Serum ferritin (log) 0.05 (−0.22-0.33) .7 
    Serum erythropoietin (log) −0.05 (−0.33-0.24) .7 
Subjects with ferritin > 25 μg/L (n = 55)   
    VHLR200W homozygosity −0.38 (−0.72 to −0.05) .026 
    Serum ferritin (log) 0.78 (0.41-1.16) .006 
    Serum erythropoietin (log) −0.31 (−0.70-0.09) .13 
Beta (95% CI)P
All subjects (n=126)*   
    VHLR200W homozygosity −0.52 (−0.74 to −0.30) < .0001 
    Serum ferritin (log) 0.43 (0.27-0.58) < .0001 
    Serum erythropoietin (log) −0.06 (−0.30-0.18) .6 
Subjects with ferritin ≤ 25 μg/L (n = 71)   
    VHLR200W homozygosity −0.42 (−0.72 to −0.13) .006 
    Serum ferritin (log) 0.05 (−0.22-0.33) .7 
    Serum erythropoietin (log) −0.05 (−0.33-0.24) .7 
Subjects with ferritin > 25 μg/L (n = 55)   
    VHLR200W homozygosity −0.38 (−0.72 to −0.05) .026 
    Serum ferritin (log) 0.78 (0.41-1.16) .006 
    Serum erythropoietin (log) −0.31 (−0.70-0.09) .13 
*

One observation was removed because of outlier (R2 = 0.58).

One observation was removed because of outlier (R2 = 0.19).

R2 = 0.53.

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