Table 1 Multivariate analysis assessing... | American Society of Hematology

Table 1

Multivariate analysis assessing the significance of SETBP1 mutations in the AAML0122 study

	EFS from study entry				OS from study entry
	N	HR	95% CI	P	HR	95% CI	P
SETBP1 mutation
No	30	1			1
Yes	13	2.92	1.17-7.29	.022	1.32	0.48-3.63	.586
Age (y)
0-1	26	1			1
2+	17	0.97	0.40-2.36	.953	2.74	0.97-7.72	.057
WBC categories (WBC × 10⁹/L)
<50	27	1			1
50+	16	0.92	0.37-2.28	.861	0.37	0.10-1.42	.148
Platelet count categories (WBC × 10⁹/L)
<50	19	1			1
50+	24	1.08	0.47-2.44	.863	0.46	0.17-1.23	.121
PTPN11 mutation
No	26	1			1
Yes	17	1.17	0.48-2.88	.728	0.79	0.29-2.16	.648
Protocol HSCT (TDV)	43	0.91	0.29-2.83	.866	0.63	0.20-1.92	.414

	EFS from study entry				OS from study entry
	N	HR	95% CI	P	HR	95% CI	P
SETBP1 mutation
No	30	1			1
Yes	13	2.92	1.17-7.29	.022	1.32	0.48-3.63	.586
Age (y)
0-1	26	1			1
2+	17	0.97	0.40-2.36	.953	2.74	0.97-7.72	.057
WBC categories (WBC × 10⁹/L)
<50	27	1			1
50+	16	0.92	0.37-2.28	.861	0.37	0.10-1.42	.148
Platelet count categories (WBC × 10⁹/L)
<50	19	1			1
50+	24	1.08	0.47-2.44	.863	0.46	0.17-1.23	.121
PTPN11 mutation
No	26	1			1
Yes	17	1.17	0.48-2.88	.728	0.79	0.29-2.16	.648
Protocol HSCT (TDV)	43	0.91	0.29-2.83	.866	0.63	0.20-1.92	.414

TDV, time-dependent variable; WT, wild-type.