Neurotoxicities in adult patients with clinical relapse (N = 201 cycles)
| . | Incidence, N (%) of cycles . | Grade I, no. of cycles . | Grade II, no. of cycles . | Grade III, no. of cycles . | Grade IV, no. of cycles . |
|---|---|---|---|---|---|
| Cognitive disturbance | 9 (4) | 3 | 0 | 1 | 5 |
| Confusion | 9 (4) | 3 | 0 | 3 | 3 |
| Consciousness impaired | 1 (0.5) | 0 | 0 | 1 | 0 |
| Dizziness | 13 (6) | 7 | 2 | 2 | 2 |
| Fatigue | 1 (0.5) | 1 | 0 | 0 | |
| Guillain-Barré–like syndrome | 1 (0.5) | 0 | 0 | 1 | 0 |
| Hallucination | 4 (2) | 0 | 0 | 2 | 2 |
| Insomnia | 2 (1) | 1 | 0 | 1 | 0 |
| Memory impaired | 7 (3) | 2 | 1 | 1 | 3 |
| Mood alteration | 12 (6) | 7 | 1 | 4 | 0 |
| Neuropathy increased | 5 (2) | 2 | 2 | 1 | 0 |
| Restlessness | 4 (2) | 1 | 2 | 0 | 1 |
| Somnolence | 1 (0.5) | 0 | 0 | 1 | 0 |
| Tremor | 4 (2) | 1 | 1 | 2 | 0 |
| . | Incidence, N (%) of cycles . | Grade I, no. of cycles . | Grade II, no. of cycles . | Grade III, no. of cycles . | Grade IV, no. of cycles . |
|---|---|---|---|---|---|
| Cognitive disturbance | 9 (4) | 3 | 0 | 1 | 5 |
| Confusion | 9 (4) | 3 | 0 | 3 | 3 |
| Consciousness impaired | 1 (0.5) | 0 | 0 | 1 | 0 |
| Dizziness | 13 (6) | 7 | 2 | 2 | 2 |
| Fatigue | 1 (0.5) | 1 | 0 | 0 | |
| Guillain-Barré–like syndrome | 1 (0.5) | 0 | 0 | 1 | 0 |
| Hallucination | 4 (2) | 0 | 0 | 2 | 2 |
| Insomnia | 2 (1) | 1 | 0 | 1 | 0 |
| Memory impaired | 7 (3) | 2 | 1 | 1 | 3 |
| Mood alteration | 12 (6) | 7 | 1 | 4 | 0 |
| Neuropathy increased | 5 (2) | 2 | 2 | 1 | 0 |
| Restlessness | 4 (2) | 1 | 2 | 0 | 1 |
| Somnolence | 1 (0.5) | 0 | 0 | 1 | 0 |
| Tremor | 4 (2) | 1 | 1 | 2 | 0 |