Table 1

Clinical characteristics of the patients

PatientSex/age, yAge at diagnosis, yPhase and BCR-ABL transcript at diagnosisTreatment 1
Treatment 2
Treatment discontinuation
BCR-ABL undetectability (blood samples)
TreatmentDuration, yYes/noTreatmentDuration, yYes/noAge at discontinuation, yOff-therapy duration, yDuration, y
F/66.7 43 CP, b3a2 IFN-α 13.3 No   Yes 55.4 11.3 5.1 
M/71.8 46 CP, b3a2 IFN-α 9.1 No   Yes 55.1 16.7 4.3 
F/72.3 57.5 CP, b3a2 IFN-α 6.5 No   Yes 64 8.3 5.8 
F/69.2 58.1 CP, b3a2 IFN-α 4.0 Yes IM 400 4.6 Yes 66.8 2.3 4.0 
F/70 61.6 CP, b3a2 IFN-α 1.3 Yes IM 400 5.0 Yes 68.1 1.9 5.1 
F/78.5 74 CP, b3a2 IM 400 4 months Yes Dasatinib* No   3.2 
PatientSex/age, yAge at diagnosis, yPhase and BCR-ABL transcript at diagnosisTreatment 1
Treatment 2
Treatment discontinuation
BCR-ABL undetectability (blood samples)
TreatmentDuration, yYes/noTreatmentDuration, yYes/noAge at discontinuation, yOff-therapy duration, yDuration, y
F/66.7 43 CP, b3a2 IFN-α 13.3 No   Yes 55.4 11.3 5.1 
M/71.8 46 CP, b3a2 IFN-α 9.1 No   Yes 55.1 16.7 4.3 
F/72.3 57.5 CP, b3a2 IFN-α 6.5 No   Yes 64 8.3 5.8 
F/69.2 58.1 CP, b3a2 IFN-α 4.0 Yes IM 400 4.6 Yes 66.8 2.3 4.0 
F/70 61.6 CP, b3a2 IFN-α 1.3 Yes IM 400 5.0 Yes 68.1 1.9 5.1 
F/78.5 74 CP, b3a2 IM 400 4 months Yes Dasatinib* No   3.2 

CP indicates chronic phase; and IM 400, imatinib 400 mg daily.

*

Dasatinib 70 mg twice daily and then 100 mg twice daily.

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