Transplantation outcome
| Characteristic . | All patients (n = 2656) . |
|---|---|
| Cumulative incidence of recurrent malignancy at 5 y, % | |
| Low-risk disease | 18 (95% CI, 16-20) |
| High-risk disease | 34 (95% CI, 32-37) |
| Cumulative incidence of nonrelapse mortality at 5 y, % | |
| Low-risk disease | 24 (95% CI, 21-26) |
| High-risk disease | 37 (95% CI, 34-39) |
| Overall survival rates at 5 y, % | |
| Low-risk disease | 66 (95% CI, 64-69) |
| High-risk disease | 32 (95% CI, 30-34) |
| Acute GVHD | |
| Days from transplantation to onset of grades II-IV GVHD, median (range) | 19 (4-302) |
| Cumulative incidence of grades II-IV GVHD at 100 d, % | 78 (95% CI, 77-80) |
| Peak grade, no. (%) | |
| Grade 0 | 465 (18) |
| Grade I | 93 (4) |
| Grade II | 1399 (53) |
| Grades III-IV | 699 (26) |
| NIH chronic GVHD (n = 932) | |
| Days from transplantation to onset, median (range) | 161 (66-1615) |
| Cumulative incidence of chronic GVHD at 2 y, % | 34 (95% CI, 32-36) |
| Type of onset, no. (%) | |
| De novo | 133 (14) |
| Quiescent or interrupted | 682 (73) |
| Progressive | 117 (13) |
| Characteristic . | All patients (n = 2656) . |
|---|---|
| Cumulative incidence of recurrent malignancy at 5 y, % | |
| Low-risk disease | 18 (95% CI, 16-20) |
| High-risk disease | 34 (95% CI, 32-37) |
| Cumulative incidence of nonrelapse mortality at 5 y, % | |
| Low-risk disease | 24 (95% CI, 21-26) |
| High-risk disease | 37 (95% CI, 34-39) |
| Overall survival rates at 5 y, % | |
| Low-risk disease | 66 (95% CI, 64-69) |
| High-risk disease | 32 (95% CI, 30-34) |
| Acute GVHD | |
| Days from transplantation to onset of grades II-IV GVHD, median (range) | 19 (4-302) |
| Cumulative incidence of grades II-IV GVHD at 100 d, % | 78 (95% CI, 77-80) |
| Peak grade, no. (%) | |
| Grade 0 | 465 (18) |
| Grade I | 93 (4) |
| Grade II | 1399 (53) |
| Grades III-IV | 699 (26) |
| NIH chronic GVHD (n = 932) | |
| Days from transplantation to onset, median (range) | 161 (66-1615) |
| Cumulative incidence of chronic GVHD at 2 y, % | 34 (95% CI, 32-36) |
| Type of onset, no. (%) | |
| De novo | 133 (14) |
| Quiescent or interrupted | 682 (73) |
| Progressive | 117 (13) |
CI indicates confidence interval; and GVHD, graft-versus-host disease.