Characteristics of related haploidentical donors and cord blood units
| Characteristic . | No. of patients (%) . | IQR 25%-75% . | Median . |
|---|---|---|---|
| Relationship of donor to recipient | |||
| Son | 15 (33) | ||
| Daughter | 5 (11) | ||
| Brother | 12 (27) | ||
| Sister | 8 (18) | ||
| Father | 4 (9) | ||
| Mother | 1 (2) | ||
| T-cell depletion device | |||
| Isolex | 26 (58) | ||
| Miltenyi | 19 (42) | ||
| Haploidentical after selection | |||
| Haplo CD34+ cells ≥ 3 × 106/kg | 27 (60) | ||
| Haplo CD3+ cells < 1 × 104/kg | 35 (78) | ||
| Cord match | |||
| 6/6 | 3 (7) | ||
| 5/6 | 33 (73) | ||
| 4/6 | 9 (20) | ||
| Haplo CD34, ×106/kg | 2.4-4.6 | 3.5 | |
| Haplo CD34 total, ×106 | 181-411 | 254 | |
| Haplo CD3 before T depletion, ×104/kg | 10 470-20 623 | 15 083 | |
| Haplo CD3 after T depletion, ×104/kg | 0.2-1.2 | 0.7 | |
| Cord TNC, ×107/kg | 1.24-2.09 | 1.55 | |
| Cord CD34, ×106/kg | 0.04-0.08 | 0.06 |
| Characteristic . | No. of patients (%) . | IQR 25%-75% . | Median . |
|---|---|---|---|
| Relationship of donor to recipient | |||
| Son | 15 (33) | ||
| Daughter | 5 (11) | ||
| Brother | 12 (27) | ||
| Sister | 8 (18) | ||
| Father | 4 (9) | ||
| Mother | 1 (2) | ||
| T-cell depletion device | |||
| Isolex | 26 (58) | ||
| Miltenyi | 19 (42) | ||
| Haploidentical after selection | |||
| Haplo CD34+ cells ≥ 3 × 106/kg | 27 (60) | ||
| Haplo CD3+ cells < 1 × 104/kg | 35 (78) | ||
| Cord match | |||
| 6/6 | 3 (7) | ||
| 5/6 | 33 (73) | ||
| 4/6 | 9 (20) | ||
| Haplo CD34, ×106/kg | 2.4-4.6 | 3.5 | |
| Haplo CD34 total, ×106 | 181-411 | 254 | |
| Haplo CD3 before T depletion, ×104/kg | 10 470-20 623 | 15 083 | |
| Haplo CD3 after T depletion, ×104/kg | 0.2-1.2 | 0.7 | |
| Cord TNC, ×107/kg | 1.24-2.09 | 1.55 | |
| Cord CD34, ×106/kg | 0.04-0.08 | 0.06 |
IQR indicates interquartile range; and TNC total nucleated cell count.