Acute toxicity
| Acute toxicity . | WHO grade 3, no. of patients/total no. . | WHO grade 4, no. of patients/total no. . | WHO grade 3 or 4, % . |
|---|---|---|---|
| Any event | 24/57 | 19/57 | 75.4 |
| Leukopenia | 13/57 | 17/57 | 52.6 |
| Infection | 11/57 | 2/57 | 22.8 |
| Anemia | 8/57 | 2/57 | 17.5 |
| Thrombopenia | 5/57 | 4/57 | 15.8 |
| Mucositis | 5/57 | 1/57 | 10.5 |
| Gastrointestinal tract disorder | 5/57 | 1/57 | 10.5 |
| Respiratory tract disorder | 3/57 | 1/57 | 7.0 |
| Heart | 4/57 | 0 | 7.0 |
| Nausea or vomiting | 3/57 | 0 | 5.3 |
| Nervous system disorder | 2/57 | 0 | 3.5 |
| Acute toxicity . | WHO grade 3, no. of patients/total no. . | WHO grade 4, no. of patients/total no. . | WHO grade 3 or 4, % . |
|---|---|---|---|
| Any event | 24/57 | 19/57 | 75.4 |
| Leukopenia | 13/57 | 17/57 | 52.6 |
| Infection | 11/57 | 2/57 | 22.8 |
| Anemia | 8/57 | 2/57 | 17.5 |
| Thrombopenia | 5/57 | 4/57 | 15.8 |
| Mucositis | 5/57 | 1/57 | 10.5 |
| Gastrointestinal tract disorder | 5/57 | 1/57 | 10.5 |
| Respiratory tract disorder | 3/57 | 1/57 | 7.0 |
| Heart | 4/57 | 0 | 7.0 |
| Nausea or vomiting | 3/57 | 0 | 5.3 |
| Nervous system disorder | 2/57 | 0 | 3.5 |