Table 3

NCI responses at respective assessment time points and best response achieved for all patients

No. on Rx/ITTEvaluation cycle
3 cycles, no. (%) 54/60*9 cycles, no. (%) 43/6015 cycles, no. (%) 38/6021 cycles, no. (%) 35/60Best response, no. (%) 60
Response      
    CR 1 (2) 3 (5) 5 (8) 6 (10) 
    CRi 2 (3) 3 (5) 3 (5) 
    nPR 6 (10) 4 (7) 5 (8) 4 (7) 
    PR 24 (40) 27 (45) 27 (45) 22 (37) 26 (43) 
ORR 24 (40) 34 (57) 36 (60) 35 (58) 39 (65) 
    DC(PR)  
No. on Rx/ITTEvaluation cycle
3 cycles, no. (%) 54/60*9 cycles, no. (%) 43/6015 cycles, no. (%) 38/6021 cycles, no. (%) 35/60Best response, no. (%) 60
Response      
    CR 1 (2) 3 (5) 5 (8) 6 (10) 
    CRi 2 (3) 3 (5) 3 (5) 
    nPR 6 (10) 4 (7) 5 (8) 4 (7) 
    PR 24 (40) 27 (45) 27 (45) 22 (37) 26 (43) 
ORR 24 (40) 34 (57) 36 (60) 35 (58) 39 (65) 
    DC(PR)  

Rx indicates therapy; ITT, intention-to-treat; nPR, nodular partial response; and DC(PR), discontinued in PR.

*

One patient not evaluable.

2008 NCI working group criteria for response.

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