Table 1

Summary of data on the expression (mRNA or protein) of GRβ in erythroblasts expanded ex vivo and on the presence of the A3669G SNP in ND and MPN patients

Ex vivo expanded erythroblasts
Blood DNA A3669G SNPTotal subjects, n/N (%)
mRNAProtein
ND 0/10 1/9 2/22 3/41 (7.3) 
Polycythemia vera 16/16 4/4* 12/22 32/41 (78) 
Essential thrombocythemia N/A N/A 1/15 1/15 (6.6) 
Primary myelofibrosis N/A N/A 7/20 7/20 (35) 
Ex vivo expanded erythroblasts
Blood DNA A3669G SNPTotal subjects, n/N (%)
mRNAProtein
ND 0/10 1/9 2/22 3/41 (7.3) 
Polycythemia vera 16/16 4/4* 12/22 32/41 (78) 
Essential thrombocythemia N/A N/A 1/15 1/15 (6.6) 
Primary myelofibrosis N/A N/A 7/20 7/20 (35) 

N/A indicates not available (not determined).

*

One of these PV patients was also analyzed for mRNA expression.

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