Table 1

Comparison of mFVIII1 and mFVIII2 with respect to PEGylation degree, specific activity, and VWF binding

PEGylation degree, mol PEG/mol FVIIISpecific activity, FVIII:C/mg proteinVWF binding, KD, nM
mFVIII1 5773 0.82 
mFVIII2 12 153 7.23 
PEGylation degree, mol PEG/mol FVIIISpecific activity, FVIII:C/mg proteinVWF binding, KD, nM
mFVIII1 5773 0.82 
mFVIII2 12 153 7.23 
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