Quantification and distribution of reads near highly induced and highly repressed genes across the TER119 transition
| Histone mark . | Cell type (across TER119 transition) . | Genes . | |||
|---|---|---|---|---|---|
| Up-regulated . | Down-regulated . | ||||
| Peak ± 95% CI . | Total ± 95% CI . | Peak ± 95% CI . | Total ± 95% CI . | ||
| H3K4me3 | CFU-Es | 152.6 ± 21.3 | 2083.1 ± 367.1 | 115.1 ± 5.8 | 1001.4 ± 89.7 |
| Erythroblasts | 220.2 ± 27.2 | 3225 ± 544.7 | 91.1 ± 4.9 | 723 ± 64.1 | |
| H3K4me2 | CFU-Es | 241.1 ± 26.5 | 4077.5 ± 635.7 | 276.4 ± 10.7 | 2437.4 ± 195 |
| Erythroblasts | 228.6 ± 23.2 | 6383.4 ± 896.1 | 186.4 ± 9.9 | 1656.4 ± 149.1 | |
| H3K9Ac | CFU-Es | 48.5 ± 9.4 | 869.9 ± 135 | 18.4 ± 1.3 | 268 ± 16.3 |
| Erythroblasts | 79.9 ± 16.1 | 1238.6 ± 214.3 | 15.7 ± 0.9 | 209.5 ± 13.1 | |
| H4K16Ac | CFU-Es | 25.3 ± 5.4 | 605.2 ± 98.2 | 14.1 ± 1.3 | 282.4 ± 37.3 |
| Erythroblasts | 43.9 ± 7.9 | 1141.7 ± 184.1 | 9.9 ± 0.6 | 254.2 ± 9.5 | |
| RNA Pol II | CFU-Es | 45.2 ± 10.7 | 611 ± 126.8 | 11.8 ± 1.3 | 198 ± 20.6 |
| Erythroblasts | 77.5 ± 15.8 | 1279.4 ± 296.9 | 12.6 ± 0.9 | 214.2 ± 13.8 | |
| H3K79me2 | CFU-Es | 24.5 ± 6 | 690.1 ± 95.7 | 16.1 ± 1.1 | 443.3 ± 25.7 |
| Erythroblasts | 42.8 ± 7.5 | 1300.8 ± 165.1 | 11.2 ± 0.7 | 336.5 ± 18.7 | |
| H3K36me3 | CFU-Es | 47 ± 8.3 | 1511.7 ± 194.7 | 7.5 ± 0.4 | 259.7 ± 12 |
| Erythroblasts | 48.8 ± 8 | 1558.7 ± 206 | 7.4 ± 0.4 | 240.7 ± 12.7 | |
| H3K27me3 | CFU-Es | 12.5 ± 3.6 | 463.9 ± 113.3 | 5.3 ± 0.7 | 223 ± 21.3 |
| Erythroblasts | 16.9 ± 3.8 | 536.7 ± 125.3 | 12 ± 1.1 | 277.5 ± 26.2 | |
| Histone mark . | Cell type (across TER119 transition) . | Genes . | |||
|---|---|---|---|---|---|
| Up-regulated . | Down-regulated . | ||||
| Peak ± 95% CI . | Total ± 95% CI . | Peak ± 95% CI . | Total ± 95% CI . | ||
| H3K4me3 | CFU-Es | 152.6 ± 21.3 | 2083.1 ± 367.1 | 115.1 ± 5.8 | 1001.4 ± 89.7 |
| Erythroblasts | 220.2 ± 27.2 | 3225 ± 544.7 | 91.1 ± 4.9 | 723 ± 64.1 | |
| H3K4me2 | CFU-Es | 241.1 ± 26.5 | 4077.5 ± 635.7 | 276.4 ± 10.7 | 2437.4 ± 195 |
| Erythroblasts | 228.6 ± 23.2 | 6383.4 ± 896.1 | 186.4 ± 9.9 | 1656.4 ± 149.1 | |
| H3K9Ac | CFU-Es | 48.5 ± 9.4 | 869.9 ± 135 | 18.4 ± 1.3 | 268 ± 16.3 |
| Erythroblasts | 79.9 ± 16.1 | 1238.6 ± 214.3 | 15.7 ± 0.9 | 209.5 ± 13.1 | |
| H4K16Ac | CFU-Es | 25.3 ± 5.4 | 605.2 ± 98.2 | 14.1 ± 1.3 | 282.4 ± 37.3 |
| Erythroblasts | 43.9 ± 7.9 | 1141.7 ± 184.1 | 9.9 ± 0.6 | 254.2 ± 9.5 | |
| RNA Pol II | CFU-Es | 45.2 ± 10.7 | 611 ± 126.8 | 11.8 ± 1.3 | 198 ± 20.6 |
| Erythroblasts | 77.5 ± 15.8 | 1279.4 ± 296.9 | 12.6 ± 0.9 | 214.2 ± 13.8 | |
| H3K79me2 | CFU-Es | 24.5 ± 6 | 690.1 ± 95.7 | 16.1 ± 1.1 | 443.3 ± 25.7 |
| Erythroblasts | 42.8 ± 7.5 | 1300.8 ± 165.1 | 11.2 ± 0.7 | 336.5 ± 18.7 | |
| H3K36me3 | CFU-Es | 47 ± 8.3 | 1511.7 ± 194.7 | 7.5 ± 0.4 | 259.7 ± 12 |
| Erythroblasts | 48.8 ± 8 | 1558.7 ± 206 | 7.4 ± 0.4 | 240.7 ± 12.7 | |
| H3K27me3 | CFU-Es | 12.5 ± 3.6 | 463.9 ± 113.3 | 5.3 ± 0.7 | 223 ± 21.3 |
| Erythroblasts | 16.9 ± 3.8 | 536.7 ± 125.3 | 12 ± 1.1 | 277.5 ± 26.2 | |