Table 1

Patient characteristics

No. (%) or median (IQR)
Patient demographics at enrollment (52 patients)  
    Median age, y (range) 42 (23-69) 
    Sex, % male 88 
    Ethnicity, % white/black/other 58/35/8 
    Serum CRP, mg/L 75 (7-136) 
    Plasma HHV8, copies/mL 30 000 (60.5-1 000 000) 
    Active MCD, % 81 
MCD-related information during follow-up (610 sample points)  
    Median serum CRP, mg/L 6 (0-24) 
    Median plasma HHV8 viral load, copies/mL 890 (0-2400) 
    Median CRP during attack 38.5 (8-110.75) 
    Median CRP during remission 3 (0-9) 
    Median plasma HHV8 viral load during attack 27 000 (2700-400 000) 
    Median plasma HHV8 viral load during remission 0 (0-1950) 
    Percent follow-up with CRP > 10 mg/L during attack 73.4 
    Percent with CRP > 10 mg/L during remission 19.6 
    Percent with detectable plasma HHV8 during attack 90.5 
    Percent with detectable plasma HHV8 during remission 38.6 
No. (%) or median (IQR)
Patient demographics at enrollment (52 patients)  
    Median age, y (range) 42 (23-69) 
    Sex, % male 88 
    Ethnicity, % white/black/other 58/35/8 
    Serum CRP, mg/L 75 (7-136) 
    Plasma HHV8, copies/mL 30 000 (60.5-1 000 000) 
    Active MCD, % 81 
MCD-related information during follow-up (610 sample points)  
    Median serum CRP, mg/L 6 (0-24) 
    Median plasma HHV8 viral load, copies/mL 890 (0-2400) 
    Median CRP during attack 38.5 (8-110.75) 
    Median CRP during remission 3 (0-9) 
    Median plasma HHV8 viral load during attack 27 000 (2700-400 000) 
    Median plasma HHV8 viral load during remission 0 (0-1950) 
    Percent follow-up with CRP > 10 mg/L during attack 73.4 
    Percent with CRP > 10 mg/L during remission 19.6 
    Percent with detectable plasma HHV8 during attack 90.5 
    Percent with detectable plasma HHV8 during remission 38.6 

IQR indicates interquartile range; CRP, C-reactive protein; HHV8, human herpesvirus-8; and MCD, multicentric Castleman disease.

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