Table 1

The North American–European Consensus Conference definition of ALI15,16 

ParameterFinding
Timing Acute onset 
Pulmonary artery occlusion pressure ≤ 18 mm Hg when measured, or lack of clinical evidence of left atrial hypertension 
Chest radiograph Bilateral infiltrates seen on frontal chest radiograph 
Hypoxemia Ratio of PaO2/FIO2 ≤ 300 mm Hg regardless of positive end-expiratory pressure level, or oxygen saturation of ≤ 90% on room air (added by NHLBI working group) 
ParameterFinding
Timing Acute onset 
Pulmonary artery occlusion pressure ≤ 18 mm Hg when measured, or lack of clinical evidence of left atrial hypertension 
Chest radiograph Bilateral infiltrates seen on frontal chest radiograph 
Hypoxemia Ratio of PaO2/FIO2 ≤ 300 mm Hg regardless of positive end-expiratory pressure level, or oxygen saturation of ≤ 90% on room air (added by NHLBI working group) 

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