Outcome of randomly assigned patients with B-precursor acute lymphoblastic leukemia with ETV6/RUNX1 and favorable trisomies
. | 5-year event-free survival mean ± SD, % . | P . | 5-year overall survival, mean ± SD, % . | P . |
---|---|---|---|---|
DT+ vs DT− (n1 = 250, n2 = 807) | 95.4 ± 1.8 vs 88.7 ± 1.5 | .002 | 98.7 ± 1.0 vs 95.5 ± 1.0 | .04 |
TEL+ vs TEL− (n1 = 358, n2 = 503) | 93.2 ± 2.2 vs 90.0 ± 2.2 | .06 | 98.6 ± 1.0 vs 95.2 ± 1.6 | .004 |
DT+ and/or TEL+ vs DT− and TEL− (n1 = 606, n2 = 199) | 94.2 ± 1.4 vs 89.0 ± 3.4 | .009 | 98.7 ± 0.7 vs 95.8 ± 2.2 | .003 |
. | 5-year event-free survival mean ± SD, % . | P . | 5-year overall survival, mean ± SD, % . | P . |
---|---|---|---|---|
DT+ vs DT− (n1 = 250, n2 = 807) | 95.4 ± 1.8 vs 88.7 ± 1.5 | .002 | 98.7 ± 1.0 vs 95.5 ± 1.0 | .04 |
TEL+ vs TEL− (n1 = 358, n2 = 503) | 93.2 ± 2.2 vs 90.0 ± 2.2 | .06 | 98.6 ± 1.0 vs 95.2 ± 1.6 | .004 |
DT+ and/or TEL+ vs DT− and TEL− (n1 = 606, n2 = 199) | 94.2 ± 1.4 vs 89.0 ± 3.4 | .009 | 98.7 ± 0.7 vs 95.8 ± 2.2 | .003 |
DT indicates trisomy 4 and trisomy 10; and TEL, ETV6/RUNX1.