Plasma cell content in BM biopsies
| Plasma cells in BM biopsy* (no. of biopsies) . | CVID Ia (n = 22) . | CVID Ib (n = 20) . | CVID II (n = 5) . | Controls (n = 14) . |
|---|---|---|---|---|
| Grade 1: absent | 11 | 4 | 1 | 0 |
| Grade 2: reduced < 3% | 9 | 16 | 3 | 0 |
| Grade 3: normal 3%- < 5% | 2 | 0 | 1 | 10 |
| Grade 4: increased ≥ 5% | 0 | 0 | 0 | 4 |
| Statistical significance (2-sided Wilcoxon-Mann-Whitney test), P | < .001 | < .001 | .006 |
| Plasma cells in BM biopsy* (no. of biopsies) . | CVID Ia (n = 22) . | CVID Ib (n = 20) . | CVID II (n = 5) . | Controls (n = 14) . |
|---|---|---|---|---|
| Grade 1: absent | 11 | 4 | 1 | 0 |
| Grade 2: reduced < 3% | 9 | 16 | 3 | 0 |
| Grade 3: normal 3%- < 5% | 2 | 0 | 1 | 10 |
| Grade 4: increased ≥ 5% | 0 | 0 | 0 | 4 |
| Statistical significance (2-sided Wilcoxon-Mann-Whitney test), P | < .001 | < .001 | .006 |