Clinical characteristics (n = 143)
| Parameter . | % (proportion) . | Value . |
|---|---|---|
| Age at diagnosis, y | 61 ± 14 | |
| Sex | 79 M:64 F | |
| LGL count, cells/μL | 2491 ± 3465 | |
| Splenomegaly % (proportion) | 38 (54/143) | |
| TCR rearrangement by PCR, % (proportion) | 97 (136/140) | |
| CD57 positive % (proportion) | 88 (126/143) | |
| Hematologic manifestation, % (proportion) | 85 (122/143) | |
| Neutropenia | 50 (72/143) | |
| Anemia | 64 (92/143) | |
| Thrombocytopenia | 33 (47/143) | |
| Multilineage cytopenia | 32 (45/143) | |
| Pancytopenia | 16 (23/143) | |
| Lymphocytosis | 27 (39/143) | |
| Lymphopenia | 19 (27/143) | |
| B-cell or antibody disorder, % (proportion) | 37 (53/143) | |
| MGUS/multiple myeloma | 11 (14/127) | |
| Hypergammaglobinemia | 14 (18/127) | |
| Hypogammaglobinemia | 8 (10/127) | |
| Chronic lymphocytic leukemia | 8 (11/143) | |
| Hairy cell | 1 (1/143) | |
| Non-Hodgkin lymphoma | 1 (2/143) | |
| B-cell lymphoma/LPD | 1 (2/143) | |
| Autoimmune disease, % (proportion) | 20 (29/143) | |
| Rheumatoid arthritis | 13 (18/143) | |
| Type II diabetes | 3 (4/143) | |
| Myasthenia gravis | 1 (2/143) | |
| Pernicious anemia | 1 (2/143) | |
| Sjögren, Crohn | 1 (2/143) | |
| Felty, polymyalgia, psoriasis | 2 (3/143) |
| Parameter . | % (proportion) . | Value . |
|---|---|---|
| Age at diagnosis, y | 61 ± 14 | |
| Sex | 79 M:64 F | |
| LGL count, cells/μL | 2491 ± 3465 | |
| Splenomegaly % (proportion) | 38 (54/143) | |
| TCR rearrangement by PCR, % (proportion) | 97 (136/140) | |
| CD57 positive % (proportion) | 88 (126/143) | |
| Hematologic manifestation, % (proportion) | 85 (122/143) | |
| Neutropenia | 50 (72/143) | |
| Anemia | 64 (92/143) | |
| Thrombocytopenia | 33 (47/143) | |
| Multilineage cytopenia | 32 (45/143) | |
| Pancytopenia | 16 (23/143) | |
| Lymphocytosis | 27 (39/143) | |
| Lymphopenia | 19 (27/143) | |
| B-cell or antibody disorder, % (proportion) | 37 (53/143) | |
| MGUS/multiple myeloma | 11 (14/127) | |
| Hypergammaglobinemia | 14 (18/127) | |
| Hypogammaglobinemia | 8 (10/127) | |
| Chronic lymphocytic leukemia | 8 (11/143) | |
| Hairy cell | 1 (1/143) | |
| Non-Hodgkin lymphoma | 1 (2/143) | |
| B-cell lymphoma/LPD | 1 (2/143) | |
| Autoimmune disease, % (proportion) | 20 (29/143) | |
| Rheumatoid arthritis | 13 (18/143) | |
| Type II diabetes | 3 (4/143) | |
| Myasthenia gravis | 1 (2/143) | |
| Pernicious anemia | 1 (2/143) | |
| Sjögren, Crohn | 1 (2/143) | |
| Felty, polymyalgia, psoriasis | 2 (3/143) |
MGUS indicates monoclonal gammopathy of undetermined significance.