Patterns of association among MCR as evaluated by applying Fisher exact test (P) followed by multiple test correction (q)
| . | Associated regions . | No. with lesion . | % with lesion . | No. without lesion . | % without lesion . | P . | q . |
|---|---|---|---|---|---|---|---|
| MALT lymphoma, 3q gain | 18q gain (BCL2, NFATC1) | 9/17 | 53 | 3/40 | 8 | .00036 | 0.0018 |
| del(17p13.1-p13.3) (TP53) | 5/17 | 29 | 0/40 | 0 | .0015 | 0.0067 | |
| 2p16.3 LOH | 3/17 | 18 | 0/40 | 0 | .023 | 0.082 | |
| 13q gain | 3/17 | 18 | 0/40 | 0 | .023 | 0.082 | |
| 5p15.2 gain | 4/17 | 23 | 1/40 | 3 | .024 | 0.082 | |
| Splenic MZL, 3q gain | 18q gain (BCL2, NFATC1) | 8/22 | 36 | 4/112 | 4 | < .00001 | 0.0003 |
| 17q22-q25.3 gain | 6/22 | 27 | 4/112 | 4 | .0014 | 0.0061 | |
| 1q gain | 5/22 | 23 | 3/112 | 3 | .0031 | 0.012 | |
| del(6q23.2-q24.1) (TNFAIP3) | 6/22 | 27 | 7/112 | 6 | .0079 | 0.027 | |
| del(6q25) | 5/22 | 23 | 3/112 | 3 | .011 | 0.035 | |
| Splenic MZL, del(7q31-q32) | del(8p12-p23) | 8/35 | 23 | 8/99 | 8 | .032 | 0.19 |
| Splenic MZL, del(17p) (TP53) | del(8p) | 8/23 | 35 | 9/111 | 8 | .002 | 0.012 |
| del(13q14.2-q14.3) (MIR15/MIR16) | 5/23 | 22 | 6/111 | 5 | .022 | 0.078 | |
| 17q22-q25.3 gain | 5/23 | 22 | 5/111 | 4 | .014 | 0.06 | |
| Splenic MZL, del(8p) | del(17p13.1-p13.3) (TP53) | 8/17 | 47 | 15/117 | 13 | .002 | 0.019 |
| del(13q14.2-q14.3) (MIR15/MIR16) | 5/17 | 29 | 6/117 | 5 | .005 | 0.034 | |
| 8q gain | 4/17 | 24 | 3/117 | 3 | .005 | 0.034 | |
| Splenic MZL, del(13q14.2-q14.3) (MIR15/MIR16) | del(6q25.2) | 4/11 | 36 | 6/123 | 5 | .004 | 0.061 |
| del(8p) | 5/11 | 45 | 11/123 | 9 | .006 | 0.062 | |
| 18q gain (BCL2, NFATC1) | 4/11 | 36 | 7/123 | 6 | .006 | 0.062 | |
| del(17p) (TP53) | 5/11 | 45 | 13/23 | 10 | .007 | 0.061 |
| . | Associated regions . | No. with lesion . | % with lesion . | No. without lesion . | % without lesion . | P . | q . |
|---|---|---|---|---|---|---|---|
| MALT lymphoma, 3q gain | 18q gain (BCL2, NFATC1) | 9/17 | 53 | 3/40 | 8 | .00036 | 0.0018 |
| del(17p13.1-p13.3) (TP53) | 5/17 | 29 | 0/40 | 0 | .0015 | 0.0067 | |
| 2p16.3 LOH | 3/17 | 18 | 0/40 | 0 | .023 | 0.082 | |
| 13q gain | 3/17 | 18 | 0/40 | 0 | .023 | 0.082 | |
| 5p15.2 gain | 4/17 | 23 | 1/40 | 3 | .024 | 0.082 | |
| Splenic MZL, 3q gain | 18q gain (BCL2, NFATC1) | 8/22 | 36 | 4/112 | 4 | < .00001 | 0.0003 |
| 17q22-q25.3 gain | 6/22 | 27 | 4/112 | 4 | .0014 | 0.0061 | |
| 1q gain | 5/22 | 23 | 3/112 | 3 | .0031 | 0.012 | |
| del(6q23.2-q24.1) (TNFAIP3) | 6/22 | 27 | 7/112 | 6 | .0079 | 0.027 | |
| del(6q25) | 5/22 | 23 | 3/112 | 3 | .011 | 0.035 | |
| Splenic MZL, del(7q31-q32) | del(8p12-p23) | 8/35 | 23 | 8/99 | 8 | .032 | 0.19 |
| Splenic MZL, del(17p) (TP53) | del(8p) | 8/23 | 35 | 9/111 | 8 | .002 | 0.012 |
| del(13q14.2-q14.3) (MIR15/MIR16) | 5/23 | 22 | 6/111 | 5 | .022 | 0.078 | |
| 17q22-q25.3 gain | 5/23 | 22 | 5/111 | 4 | .014 | 0.06 | |
| Splenic MZL, del(8p) | del(17p13.1-p13.3) (TP53) | 8/17 | 47 | 15/117 | 13 | .002 | 0.019 |
| del(13q14.2-q14.3) (MIR15/MIR16) | 5/17 | 29 | 6/117 | 5 | .005 | 0.034 | |
| 8q gain | 4/17 | 24 | 3/117 | 3 | .005 | 0.034 | |
| Splenic MZL, del(13q14.2-q14.3) (MIR15/MIR16) | del(6q25.2) | 4/11 | 36 | 6/123 | 5 | .004 | 0.061 |
| del(8p) | 5/11 | 45 | 11/123 | 9 | .006 | 0.062 | |
| 18q gain (BCL2, NFATC1) | 4/11 | 36 | 7/123 | 6 | .006 | 0.062 | |
| del(17p) (TP53) | 5/11 | 45 | 13/23 | 10 | .007 | 0.061 |