Table 2

Correlation P values of SET protein isoform immunoblot densities with CLL prognostic parameters

Rai stage* (n = 281)CD38 (n = 285)IGVH (n = 284)Zap-70 (n = 262)17p del (n = 31)13q del (n = 129)11q del (n = 33)Trisomy 12 (n = 38)
SETβ-isoform .173 .289 .347 .405 .632 .705 .810 .881 
SETα-isoform .017 .161 .0006 .142 .183 .318 .684 .523 
Total SET(α + β) .033 .877 .007 .483 .456 .813 .762 .803 
α/β ratio .598 .004 .002 .193 .620 .087 .837 .177 
Rai stage* (n = 281)CD38 (n = 285)IGVH (n = 284)Zap-70 (n = 262)17p del (n = 31)13q del (n = 129)11q del (n = 33)Trisomy 12 (n = 38)
SETβ-isoform .173 .289 .347 .405 .632 .705 .810 .881 
SETα-isoform .017 .161 .0006 .142 .183 .318 .684 .523 
Total SET(α + β) .033 .877 .007 .483 .456 .813 .762 .803 
α/β ratio .598 .004 .002 .193 .620 .087 .837 .177 
*

P by ANOVA.

P by Wilcoxon and χ2 tests.

n = 222 total with cytogenetic determinations.

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