Distribution of the subgroup defined on the basis of the properties (drop of the miR-181b expression values of ≥ 50% between the first and the last point and/or value ≤ 0.005 at the starting point), IGHV mutational status and ZAP-70 expression in progressive and stable CLL
| Subgroup . | Training set . | P* . | Validation set . | P* . | ||
|---|---|---|---|---|---|---|
| Progressive (N = 23) . | Stable (N = 13) . | Progressive (N = 30) . | Stable (N = 48) . | |||
| With properties | 19 | 4 | .004 | 22 | 7 | < .001 |
| IGHV unmutated | 10 | 3 | .3 | 18 | 6 | < .001 |
| ZAP-positive cells ≥ 20% | 9 | 3 | .5 | 17 | 12 | .008 |
| Subgroup . | Training set . | P* . | Validation set . | P* . | ||
|---|---|---|---|---|---|---|
| Progressive (N = 23) . | Stable (N = 13) . | Progressive (N = 30) . | Stable (N = 48) . | |||
| With properties | 19 | 4 | .004 | 22 | 7 | < .001 |
| IGHV unmutated | 10 | 3 | .3 | 18 | 6 | < .001 |
| ZAP-positive cells ≥ 20% | 9 | 3 | .5 | 17 | 12 | .008 |
P values were calculated by the Fisher exact test.