Table 9

Global Response Score for LYP and PCALCL

Global Score*DefinitionSkinNodeViscera
LYP     
    CR Complete disappearance of all clinical evidence of disease CR CR or NI NI 
    PR Regression of measurable disease CR No CR but no PD NI 
  PR No PD NI 
    SD Failure to attain CR, PR, or PD representative of all disease SD or IDA (Table 8, point I) No PD NI 
    PD Progressive disease PD in any category PD in any category PD in any category 
    Relapse Recurrence disease in prior CR Relapse in any category Relapse in any category Relapse in any category 
PCALCL     
    CR Complete disappearance of all clinical evidence of disease CR Both categories have CR or NI Both categories have CR or NI 
    PR Regression of measurable disease CR Both categories do not have a CR or NI but no PD Both categories do not have a CR or NI but no PD 
  PR No category has a PD; and if either category is involved at baseline, at least one has a CR or PR No category has a PD; and if either category is involved at baseline, at least one has a CR or PR 
    SD Failure to attain CR, PR, or PD representative of all disease PR No category has a PD; and if either is involved at baseline, no CR or PR in either No category has a PD; and if either is involved at baseline, no CR or PR in either 
   CR/NI, PR, OR SD in any category and neither category has a PD CR/NI, PR, OR SD in any category and neither category has a PD 
    PD Progressive disease PD in any category PD in any category PD in any category 
    Relapse Recurrence disease in prior CR Relapse in any category Relapse in any category Relapse in any category 
Global Score*DefinitionSkinNodeViscera
LYP     
    CR Complete disappearance of all clinical evidence of disease CR CR or NI NI 
    PR Regression of measurable disease CR No CR but no PD NI 
  PR No PD NI 
    SD Failure to attain CR, PR, or PD representative of all disease SD or IDA (Table 8, point I) No PD NI 
    PD Progressive disease PD in any category PD in any category PD in any category 
    Relapse Recurrence disease in prior CR Relapse in any category Relapse in any category Relapse in any category 
PCALCL     
    CR Complete disappearance of all clinical evidence of disease CR Both categories have CR or NI Both categories have CR or NI 
    PR Regression of measurable disease CR Both categories do not have a CR or NI but no PD Both categories do not have a CR or NI but no PD 
  PR No category has a PD; and if either category is involved at baseline, at least one has a CR or PR No category has a PD; and if either category is involved at baseline, at least one has a CR or PR 
    SD Failure to attain CR, PR, or PD representative of all disease PR No category has a PD; and if either is involved at baseline, no CR or PR in either No category has a PD; and if either is involved at baseline, no CR or PR in either 
   CR/NI, PR, OR SD in any category and neither category has a PD CR/NI, PR, OR SD in any category and neither category has a PD 
    PD Progressive disease PD in any category PD in any category PD in any category 
    Relapse Recurrence disease in prior CR Relapse in any category Relapse in any category Relapse in any category 

NI indicates noninvolved.

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