Characteristics of patients (n = 345)
| Characteristic/category . | No. . | % . |
|---|---|---|
| Age, y | ||
| Median (range) | 57 (15-92) | |
| ≤ 60 | 204 | 59.1 |
| > 60 | 141 | 40.9 |
| Sex | ||
| Male | 214 | 62.0 |
| Female | 131 | 38.0 |
| Performance status | ||
| ECOG 0/1 | 287 | 83.2 |
| ECOG ≥ 2 | 58 | 16.8 |
| Serum LDH level | ||
| Normal | 206 | 59.7 |
| Increased | 133 | 38.6 |
| Missing | 6 | 1.7 |
| B symptoms | ||
| Absent | 279 | 80.9 |
| Present | 65 | 18.8 |
| Missing | 1 | 0.3 |
| Extranodal involvements | ||
| < 2 | 267 | 77.4 |
| ≥ 2 | 78 | 22.6 |
| IPI | ||
| Low/low to intermediate | 204/55 | 59.1/15.9 |
| High to intermediate/high | 53/27 | 15.4/7.8 |
| Missing | 6 | 1.7 |
| Lugano stage | ||
| I | 78 | 22.6 |
| II-1 | 106 | 30.7 |
| II-2 | 68 | 19.7 |
| II-E | 14 | 4.1 |
| IV | 79 | 22.9 |
| Bulky disease | ||
| Bulky | 73 | 21.2 |
| Nonbulky | 272 | 78.8 |
| Bone marrow invasion | ||
| Absent | 306 | 88.7 |
| Present | 16 | 4.6 |
| Not evaluated | 23 | 6.7 |
| Location | ||
| Duodenum | 12 | 3.5 |
| Jejunum/ileum | 17/63 | 4.9/18.3 |
| Ileocecum/ascending colon | 175/37 | 50.7/10.7 |
| Transverse/descending colon | 11/3 | 3.2/0.9 |
| Rectosigmoid colon | 14 | 4.0 |
| Multiple sites | 13 | 3.8 |
| Treatment modality | ||
| Surgery/CTx | 188 | 54.5 |
| CTx | 139 | 40.3 |
| Surgery | 12 | 3.5 |
| No treatment | 6 | 1.7 |
| CTx regimen | ||
| CHOP | 134 | 38.8 |
| R-CHOP | 172 | 49.9 |
| Others | 21 | 6.1 |
| Characteristic/category . | No. . | % . |
|---|---|---|
| Age, y | ||
| Median (range) | 57 (15-92) | |
| ≤ 60 | 204 | 59.1 |
| > 60 | 141 | 40.9 |
| Sex | ||
| Male | 214 | 62.0 |
| Female | 131 | 38.0 |
| Performance status | ||
| ECOG 0/1 | 287 | 83.2 |
| ECOG ≥ 2 | 58 | 16.8 |
| Serum LDH level | ||
| Normal | 206 | 59.7 |
| Increased | 133 | 38.6 |
| Missing | 6 | 1.7 |
| B symptoms | ||
| Absent | 279 | 80.9 |
| Present | 65 | 18.8 |
| Missing | 1 | 0.3 |
| Extranodal involvements | ||
| < 2 | 267 | 77.4 |
| ≥ 2 | 78 | 22.6 |
| IPI | ||
| Low/low to intermediate | 204/55 | 59.1/15.9 |
| High to intermediate/high | 53/27 | 15.4/7.8 |
| Missing | 6 | 1.7 |
| Lugano stage | ||
| I | 78 | 22.6 |
| II-1 | 106 | 30.7 |
| II-2 | 68 | 19.7 |
| II-E | 14 | 4.1 |
| IV | 79 | 22.9 |
| Bulky disease | ||
| Bulky | 73 | 21.2 |
| Nonbulky | 272 | 78.8 |
| Bone marrow invasion | ||
| Absent | 306 | 88.7 |
| Present | 16 | 4.6 |
| Not evaluated | 23 | 6.7 |
| Location | ||
| Duodenum | 12 | 3.5 |
| Jejunum/ileum | 17/63 | 4.9/18.3 |
| Ileocecum/ascending colon | 175/37 | 50.7/10.7 |
| Transverse/descending colon | 11/3 | 3.2/0.9 |
| Rectosigmoid colon | 14 | 4.0 |
| Multiple sites | 13 | 3.8 |
| Treatment modality | ||
| Surgery/CTx | 188 | 54.5 |
| CTx | 139 | 40.3 |
| Surgery | 12 | 3.5 |
| No treatment | 6 | 1.7 |
| CTx regimen | ||
| CHOP | 134 | 38.8 |
| R-CHOP | 172 | 49.9 |
| Others | 21 | 6.1 |
LDH indicates lactate dehydrogenase; and CTx, chemotherapy.