Clinical and epidemiologic characteristics of HCQ-treated patients
Parameter . | HCQ patients (n = 20)* . |
---|---|
Age, y | 49.78 ± 2.92 (28-68) |
Sex (male/female) | 14/6 |
HIV infection | 5.33 ± 1.38 (1-15) |
Duration of ART, y | 4.43 ± 1.22 (1-15) |
Viral load, copies HIV RNA/mL* | |
Baseline | < 37 |
6 mo of HCQ | < 37 |
2 mo after HCQ interruption | < 37 |
Coinfections, n (%) | |
HBV | 1/20 (5) |
HCV | 4/20 (20) |
CD4+ T-cell count nadir, cells/mm3 | 54.57 ± 11.43 (6-112) |
CD4+ T cells, % | 10.68 ± 1.07 (3.8-18.2) |
CD4+ T-cell counts, cells/mm3 | 143.70 ± 13.19 (6-200) |
Total lymphocyte count, mean ± SE, cells/mm3* | |
Baseline | 1403.33 ± 171.07 |
6 mo of HCQ | 1338.33 ± 145.25 |
2 mo after HCQ interruption | 1304.45 ± 149.65 |
ART treatment, n | |
PI | 10 |
NNRTI | 7 |
Other | 3 |
Parameter . | HCQ patients (n = 20)* . |
---|---|
Age, y | 49.78 ± 2.92 (28-68) |
Sex (male/female) | 14/6 |
HIV infection | 5.33 ± 1.38 (1-15) |
Duration of ART, y | 4.43 ± 1.22 (1-15) |
Viral load, copies HIV RNA/mL* | |
Baseline | < 37 |
6 mo of HCQ | < 37 |
2 mo after HCQ interruption | < 37 |
Coinfections, n (%) | |
HBV | 1/20 (5) |
HCV | 4/20 (20) |
CD4+ T-cell count nadir, cells/mm3 | 54.57 ± 11.43 (6-112) |
CD4+ T cells, % | 10.68 ± 1.07 (3.8-18.2) |
CD4+ T-cell counts, cells/mm3 | 143.70 ± 13.19 (6-200) |
Total lymphocyte count, mean ± SE, cells/mm3* | |
Baseline | 1403.33 ± 171.07 |
6 mo of HCQ | 1338.33 ± 145.25 |
2 mo after HCQ interruption | 1304.45 ± 149.65 |
ART treatment, n | |
PI | 10 |
NNRTI | 7 |
Other | 3 |
Data are presented as mean ± SE (range) except where noted.
HBV indicates hepatitis B virus; HCV, hepatitis C virus; NNRTI, nonnucleoside reverse transcriptase inhibitor; and PI, protease inhibitor
No significant differences were detected.