Table 1

Clinical and epidemiologic characteristics of HCQ-treated patients

ParameterHCQ patients (n = 20)*
Age, y 49.78 ± 2.92 (28-68) 
Sex (male/female) 14/6 
HIV infection 5.33 ± 1.38 (1-15) 
Duration of ART, y 4.43 ± 1.22 (1-15) 
Viral load, copies HIV RNA/mL*  
    Baseline < 37 
    6 mo of HCQ < 37 
    2 mo after HCQ interruption < 37 
Coinfections, n (%)  
    HBV 1/20 (5) 
    HCV 4/20 (20) 
CD4+ T-cell count nadir, cells/mm3 54.57 ± 11.43 (6-112) 
CD4+ T cells, % 10.68 ± 1.07 (3.8-18.2) 
CD4+ T-cell counts, cells/mm3 143.70 ± 13.19 (6-200) 
Total lymphocyte count, mean ± SE, cells/mm3*  
    Baseline 1403.33 ± 171.07 
    6 mo of HCQ 1338.33 ± 145.25 
    2 mo after HCQ interruption 1304.45 ± 149.65 
ART treatment, n  
    PI 10 
    NNRTI 
    Other 
ParameterHCQ patients (n = 20)*
Age, y 49.78 ± 2.92 (28-68) 
Sex (male/female) 14/6 
HIV infection 5.33 ± 1.38 (1-15) 
Duration of ART, y 4.43 ± 1.22 (1-15) 
Viral load, copies HIV RNA/mL*  
    Baseline < 37 
    6 mo of HCQ < 37 
    2 mo after HCQ interruption < 37 
Coinfections, n (%)  
    HBV 1/20 (5) 
    HCV 4/20 (20) 
CD4+ T-cell count nadir, cells/mm3 54.57 ± 11.43 (6-112) 
CD4+ T cells, % 10.68 ± 1.07 (3.8-18.2) 
CD4+ T-cell counts, cells/mm3 143.70 ± 13.19 (6-200) 
Total lymphocyte count, mean ± SE, cells/mm3*  
    Baseline 1403.33 ± 171.07 
    6 mo of HCQ 1338.33 ± 145.25 
    2 mo after HCQ interruption 1304.45 ± 149.65 
ART treatment, n  
    PI 10 
    NNRTI 
    Other 

Data are presented as mean ± SE (range) except where noted.

HBV indicates hepatitis B virus; HCV, hepatitis C virus; NNRTI, nonnucleoside reverse transcriptase inhibitor; and PI, protease inhibitor

*

No significant differences were detected.

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