Mutational analysis
| Gene/sample no. . | Mutation . | |||
|---|---|---|---|---|
| Location . | Nucleotide change* . | . | aa change† . | |
| FOXO3 | ||||
| 8 | Exon 1 | C366G | Missense | P8 → R |
| 11 | Exon 2 | A2279T | Missense | I646 → F |
| 21 | Exon 1 | G669A | Missense | G109 → E |
| PRDM1 | ||||
| 24 | Exon 4 | C864A | Nonsense | Y174 → STOP |
| NK92 | Exon 5 | C951A | Nonsense | C203 → STOP |
| Gene/sample no. . | Mutation . | |||
|---|---|---|---|---|
| Location . | Nucleotide change* . | . | aa change† . | |
| FOXO3 | ||||
| 8 | Exon 1 | C366G | Missense | P8 → R |
| 11 | Exon 2 | A2279T | Missense | I646 → F |
| 21 | Exon 1 | G669A | Missense | G109 → E |
| PRDM1 | ||||
| 24 | Exon 4 | C864A | Nonsense | Y174 → STOP |
| NK92 | Exon 5 | C951A | Nonsense | C203 → STOP |
Nucleotide position +1 equivalents to the first nucleotide of GenBank accession number NM_001198.3 (PRDM1) or GenBank accession number NM_001455.3 (FOXO3).
Amino acid location refers to GenBank accession number NP_001189 (PRDM1) and NP_001146.1 (FOXO3).