Table 3

Change in fatigue 6 weeks after treatment initiation with intravenous iron or intravenous placebo in dependence of the serum ferritin concentration at baseline

Iron groupPlacebo groupP
Baseline ferritin ≤ 15 ng/mL (n = 34)    
    Change of fatigue (BFI), median −1.8 (−2.5, −0.8) −0.4 (−1.2, 0.0) .005 
    Fatigue improved (SPI), n (%) 14/17 (82%) 8/17 (47%) .03 
Baseline ferritin > 15 ng/mL (n = 56)    
    Change of fatigue (BFI), median −0.7 (−1.8, 0.0) −0.8 (−1.4, 0.0) ns 
    Fatigue improved (SPI), n (%) 14/26 (54%) 11/30 (37%) ns 
Iron groupPlacebo groupP
Baseline ferritin ≤ 15 ng/mL (n = 34)    
    Change of fatigue (BFI), median −1.8 (−2.5, −0.8) −0.4 (−1.2, 0.0) .005 
    Fatigue improved (SPI), n (%) 14/17 (82%) 8/17 (47%) .03 
Baseline ferritin > 15 ng/mL (n = 56)    
    Change of fatigue (BFI), median −0.7 (−1.8, 0.0) −0.8 (−1.4, 0.0) ns 
    Fatigue improved (SPI), n (%) 14/26 (54%) 11/30 (37%) ns 

Results are presented as median values (quartiles Q1, Q3) or number of patients (%). P values were calculated with the Mann Whitney U test or the χ2 test.

ns indicates not significant and no trend (P > .10).

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