Examples of α- and β-duplexes
| . | α-duplexes . | β-duplexes . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Ratio (miRNA/miRNA*) | let-7a | miR-103 | miR-320a | miR-107 | miR-101 | miR-30e | miR-17 | miR-30a | miR-32 | miR-625 |
| Mouse leukemia 1 | 15773.5 | 40465 | 9354 | 21195 | 1881 | 0.754216867 | 1.703703704 | N/E | N/E | N/E |
| Mouse leukemia 2 | 31822.66667 | 26642 | 5505 | 16623 | 1237 | 0.828804348 | 1.508274232 | N/E | N/E | N/E |
| ES undiff | 11179 | 207069 | 25214 | 20119 | 8012 | 0.141397289 | 4.563953488 | 2.751046025 | 0.888888889 | 0.581699346 |
| ES diff | 4986 | 269177 | 2228 | 19099 | 3880 | 0.365884431 | 2.691432904 | 3.246661102 | 1.636363636 | 0.520958084 |
| Leukemia 1 | 6349 | 46489 | 37114 | 32102 | 19329 | 0.013737836 | 0.655882353 | 0.5 | 3 | 1.474358974 |
| Leukemia 2 | 5364.58 | 68834 | 8378.5 | 17958 | 6974 | 1.716995682 | 1.081261596 | 2.735955056 | 5.538461538 | 0.785714286 |
| Leukemia 3 | 2701.321839 | 31017 | 3095 | 11571 | 5629 | 0.849372385 | 1.05952381 | 0.230769231 | 3.75 | 0.388888889 |
| Prostate 1 | 47738 | 35289 | 2782 | 7347 | 2555 | 0.235474006 | 3.344827586 | 2.492537313 | 2.166666667 | 1.4 |
| Prostate 2 | 14021.92308 | 31233 | 2090 | 9151 | 1676 | 0.153729072 | 7.416149068 | 1.145530146 | 1.8 | 6.428571429 |
| Colon | 16389.34043 | 309168 | 109730 | 6041 | 25246 | 0.974157734 | 8.263414634 | 3.492307692 | 1.6 | 1.125 |
| . | α-duplexes . | β-duplexes . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Ratio (miRNA/miRNA*) | let-7a | miR-103 | miR-320a | miR-107 | miR-101 | miR-30e | miR-17 | miR-30a | miR-32 | miR-625 |
| Mouse leukemia 1 | 15773.5 | 40465 | 9354 | 21195 | 1881 | 0.754216867 | 1.703703704 | N/E | N/E | N/E |
| Mouse leukemia 2 | 31822.66667 | 26642 | 5505 | 16623 | 1237 | 0.828804348 | 1.508274232 | N/E | N/E | N/E |
| ES undiff | 11179 | 207069 | 25214 | 20119 | 8012 | 0.141397289 | 4.563953488 | 2.751046025 | 0.888888889 | 0.581699346 |
| ES diff | 4986 | 269177 | 2228 | 19099 | 3880 | 0.365884431 | 2.691432904 | 3.246661102 | 1.636363636 | 0.520958084 |
| Leukemia 1 | 6349 | 46489 | 37114 | 32102 | 19329 | 0.013737836 | 0.655882353 | 0.5 | 3 | 1.474358974 |
| Leukemia 2 | 5364.58 | 68834 | 8378.5 | 17958 | 6974 | 1.716995682 | 1.081261596 | 2.735955056 | 5.538461538 | 0.785714286 |
| Leukemia 3 | 2701.321839 | 31017 | 3095 | 11571 | 5629 | 0.849372385 | 1.05952381 | 0.230769231 | 3.75 | 0.388888889 |
| Prostate 1 | 47738 | 35289 | 2782 | 7347 | 2555 | 0.235474006 | 3.344827586 | 2.492537313 | 2.166666667 | 1.4 |
| Prostate 2 | 14021.92308 | 31233 | 2090 | 9151 | 1676 | 0.153729072 | 7.416149068 | 1.145530146 | 1.8 | 6.428571429 |
| Colon | 16389.34043 | 309168 | 109730 | 6041 | 25246 | 0.974157734 | 8.263414634 | 3.492307692 | 1.6 | 1.125 |
N/E indicates not expressed; ES undiff, undifferentiated embryonic stem cells; and ES diff, differentiated embryonic stem cells..