Association of individual chromosomal aberrations with JAK2 mutational status
| Aberration type . | JAK2 mutant (n = 297) . | JAK2 wild-type (n = 111) . | P . | P* . | |
|---|---|---|---|---|---|
| UPD | 9p | 169 (56.90%) | 0 (0.00%) | 1.35 × 10−32 | 3.38 × 10−31 |
| UPD | 1p | 2 (0.67%) | 6 (5.41%) | .0062 | .1548 |
| deletion | 12p | 2 (0.67%) | 4 (3.60%) | .0492 | 1 |
| gain | 9p | 6 (2.02%) | 0 (0.00%) | .1959 | 1 |
| trisomy | 9 | 9 (3.03%) | 1 (0.90%) | .2983 | 1 |
| UPD | 7q | 2 (0.67%) | 2 (1.80%) | .2990 | 1 |
| deletion | 3p | 5 (1.68%) | 0 (0.00%) | .3293 | 1 |
| deletion | 4q | 11 (3.70%) | 2 (1.80%) | .5278 | 1 |
| deletion | 11q | 4 (1.35%) | 0 (0.00%) | .5783 | 1 |
| deletion | 5q | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| deletion | 6p | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| UPD | 22q | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| deletion | 12q | 4 (1.35%) | 2 (1.80%) | .6653 | 1 |
| UPD | 14q | 7 (2.36%) | 1 (0.90%) | .6888 | 1 |
| gain | 1q | 11 (3.70%) | 3 (2.70%) | .7668 | 1 |
| deletion | 13q | 11 (3.70%) | 3 (2.70%) | .7668 | 1 |
| deletion | 20q | 11 (3.70%) | 5 (4.50%) | .7752 | 1 |
| gain | 3q | 3 (1.01%) | 1 (0.90%) | 1 | 1 |
| deletion | 7q | 7 (2.36%) | 3 (2.70%) | 1 | 1 |
| deletion | 7p | 3 (1.01%) | 1 (0.90%) | 1 | 1 |
| trisomy | 8 | 6 (2.02%) | 2 (1.80%) | 1 | 1 |
| UPD | 11q | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
| deletion | 18p | 4 (1.35%) | 1 (0.90%) | 1 | 1 |
| UPD | 19q | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
| trisomy | 21 | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
| Aberration type . | JAK2 mutant (n = 297) . | JAK2 wild-type (n = 111) . | P . | P* . | |
|---|---|---|---|---|---|
| UPD | 9p | 169 (56.90%) | 0 (0.00%) | 1.35 × 10−32 | 3.38 × 10−31 |
| UPD | 1p | 2 (0.67%) | 6 (5.41%) | .0062 | .1548 |
| deletion | 12p | 2 (0.67%) | 4 (3.60%) | .0492 | 1 |
| gain | 9p | 6 (2.02%) | 0 (0.00%) | .1959 | 1 |
| trisomy | 9 | 9 (3.03%) | 1 (0.90%) | .2983 | 1 |
| UPD | 7q | 2 (0.67%) | 2 (1.80%) | .2990 | 1 |
| deletion | 3p | 5 (1.68%) | 0 (0.00%) | .3293 | 1 |
| deletion | 4q | 11 (3.70%) | 2 (1.80%) | .5278 | 1 |
| deletion | 11q | 4 (1.35%) | 0 (0.00%) | .5783 | 1 |
| deletion | 5q | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| deletion | 6p | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| UPD | 22q | 3 (1.01%) | 2 (1.80%) | .6164 | 1 |
| deletion | 12q | 4 (1.35%) | 2 (1.80%) | .6653 | 1 |
| UPD | 14q | 7 (2.36%) | 1 (0.90%) | .6888 | 1 |
| gain | 1q | 11 (3.70%) | 3 (2.70%) | .7668 | 1 |
| deletion | 13q | 11 (3.70%) | 3 (2.70%) | .7668 | 1 |
| deletion | 20q | 11 (3.70%) | 5 (4.50%) | .7752 | 1 |
| gain | 3q | 3 (1.01%) | 1 (0.90%) | 1 | 1 |
| deletion | 7q | 7 (2.36%) | 3 (2.70%) | 1 | 1 |
| deletion | 7p | 3 (1.01%) | 1 (0.90%) | 1 | 1 |
| trisomy | 8 | 6 (2.02%) | 2 (1.80%) | 1 | 1 |
| UPD | 11q | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
| deletion | 18p | 4 (1.35%) | 1 (0.90%) | 1 | 1 |
| UPD | 19q | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
| trisomy | 21 | 2 (0.67%) | 1 (0.90%) | 1 | 1 |
After Bonferroni correction for multiple testing; significant associations are bold.