Arsenic binding proteins
| Proteins and references . | Disease or cell lines . | Category . | Functions . |
|---|---|---|---|
| PML79 | APL | Phosphoprotein; scaffold protein | Tumor suppressor; probable transcription factor |
| c-CBL83 | CML, K562 cells | Ubiquitin E3 ligase | Proteolysis |
| SIAH183 | CML, K562 cells | Ubiquitin E3 ligase | Proteolysis |
| Trx R84 | MCF-7 cells | Oxidoreductase | Redox regulation |
| GSR85 | Arsenic toxication | Oxidoreductase | Redox regulation |
| TPX-2 II86 | Ovary cells | Peroxidase | Redox regulation |
| PDI87 | Fibrosarcoma cells | Oxidoreductase | Redox regulation |
| MTs88 | Arsenic detoxication | Metallothioneins | Binding heavy metals |
| MTF189 | Arsenic detoxication | Transcription factor | Activation of metallothionein transcription |
| Keap127 | hepa1c1c7 cells | Phosphoprotein | Transcription regulation |
| Tubulins90-92 | K562 cells | Cell skeleton proteins | Structural subunit of microtubules |
| β-Actin91-93 | K562 and MCF-7 cells | Cell skeleton proteins | Cytoskeleton |
| PPM1D94 | Malignancies | Phosphatase; oncoprotein | Protein serine/threonine phosphatase; regulation of cell cycle |
| JNK phosphatase26 | Carcinogenesis | Dual specificity protein phosphatase | Cellular signaling |
| Iκ B95 | Inflammation and carcinogenesis | Protein kinase | Regulation of NFκB pathway |
| Galectin-186,96 | Ovary cells | Pyruvate kinase | Regulation of NFκB pathway |
| PKM291 | MCF-7 cells | Phosphoprotein | Glycolysis |
| Hemoglobin97 | Red blood cells | Globin family | Oxygen transport |
| Proteins and references . | Disease or cell lines . | Category . | Functions . |
|---|---|---|---|
| PML79 | APL | Phosphoprotein; scaffold protein | Tumor suppressor; probable transcription factor |
| c-CBL83 | CML, K562 cells | Ubiquitin E3 ligase | Proteolysis |
| SIAH183 | CML, K562 cells | Ubiquitin E3 ligase | Proteolysis |
| Trx R84 | MCF-7 cells | Oxidoreductase | Redox regulation |
| GSR85 | Arsenic toxication | Oxidoreductase | Redox regulation |
| TPX-2 II86 | Ovary cells | Peroxidase | Redox regulation |
| PDI87 | Fibrosarcoma cells | Oxidoreductase | Redox regulation |
| MTs88 | Arsenic detoxication | Metallothioneins | Binding heavy metals |
| MTF189 | Arsenic detoxication | Transcription factor | Activation of metallothionein transcription |
| Keap127 | hepa1c1c7 cells | Phosphoprotein | Transcription regulation |
| Tubulins90-92 | K562 cells | Cell skeleton proteins | Structural subunit of microtubules |
| β-Actin91-93 | K562 and MCF-7 cells | Cell skeleton proteins | Cytoskeleton |
| PPM1D94 | Malignancies | Phosphatase; oncoprotein | Protein serine/threonine phosphatase; regulation of cell cycle |
| JNK phosphatase26 | Carcinogenesis | Dual specificity protein phosphatase | Cellular signaling |
| Iκ B95 | Inflammation and carcinogenesis | Protein kinase | Regulation of NFκB pathway |
| Galectin-186,96 | Ovary cells | Pyruvate kinase | Regulation of NFκB pathway |
| PKM291 | MCF-7 cells | Phosphoprotein | Glycolysis |
| Hemoglobin97 | Red blood cells | Globin family | Oxygen transport |