Outcome of patients with APL treated with ATO-based regimens since 2006
| Year . | Author . | No. . | Regimen . | CR, % . | EFS, %* . | DFS, %* . | OS, %* . |
|---|---|---|---|---|---|---|---|
| 2010 | Powell et al59 | 244 (237 standard controls) | Induction: ATRA/CT; consolidation: ATRA/CT/ATO | 90 | 80 (3 y) | 90 (3 y) | 86 (3 y) |
| 2010 | Zhou et al58 | 19 (age ≤ 15) | ATO | 89.5 | 72.7 | NR | 83.9 |
| 2010 | Mathews et al57 | 72 | ATO | 86.1 | 69 | 80 | 74.2 |
| 2009 | Dai et al60 | 90 | ATO/ATRA | 93.3 | 92.2 (3 y) | ||
| 2006 | Ghavamzadeh et al61 | 111 | ATO | 85.6 | NR | 63.7 (2 y) | 87.6 (3 y) |
| 2008 | Hu et al39 | 85 | ATO/ATRA/CT | 94.1 | 89.2 | NR | 91.7 |
| 2007 | Wu et al62 | 114 | As4S4/ATRA or As4S4/CT | 94 (4 y) |
| Year . | Author . | No. . | Regimen . | CR, % . | EFS, %* . | DFS, %* . | OS, %* . |
|---|---|---|---|---|---|---|---|
| 2010 | Powell et al59 | 244 (237 standard controls) | Induction: ATRA/CT; consolidation: ATRA/CT/ATO | 90 | 80 (3 y) | 90 (3 y) | 86 (3 y) |
| 2010 | Zhou et al58 | 19 (age ≤ 15) | ATO | 89.5 | 72.7 | NR | 83.9 |
| 2010 | Mathews et al57 | 72 | ATO | 86.1 | 69 | 80 | 74.2 |
| 2009 | Dai et al60 | 90 | ATO/ATRA | 93.3 | 92.2 (3 y) | ||
| 2006 | Ghavamzadeh et al61 | 111 | ATO | 85.6 | NR | 63.7 (2 y) | 87.6 (3 y) |
| 2008 | Hu et al39 | 85 | ATO/ATRA/CT | 94.1 | 89.2 | NR | 91.7 |
| 2007 | Wu et al62 | 114 | As4S4/ATRA or As4S4/CT | 94 (4 y) |
NR indicates not reported.
Five years, unless otherwise indicated.