Table 3

Association between SNPs, VWF:Ag levels, and VWF:CB activity

SNP IDVWF:Ag levels (± SE)PqVWF:CB activity (± SE)Pq
rs10849385 −0.003 (± 0.022) .88 0.90 0.008 (± 0.026) .76 0.70 
rs7306706 −0.043 (± 0.021) .04 0.42 −0.037 (± 0.025) .14 0.58 
rs1610056 −0.004 (± 0.032) .90 0.90 −0.001 (± 0.038) .98 0.74 
rs2238103 −0.012 (± 0.022) .59 0.87 −0.027 (± 0.026) .32 0.58 
rs1800378 0.019 (± 0.022) .39 0.87 0.033 (± 0.026) .21 0.58 
rs7139057 −0.014 (± 0.027) .60 0.87 −0.035 (± 0.032) .27 0.58 
rs216293 0.005 (± 0.022) .81 0.90 −0.011 (± 0.026) .66 0.70 
rs1063857 0.039 (± 0.022) .08 0.48 0.030 (± 0.027) .26 0.58 
rs216340 0.004 (± 0.026) .87 0.90 −0.007 (± 0.031) .82 0.70 
rs12810426 0.004 (± 0.025) .88 0.90 −0.037 (± 0.030) .22 0.58 
rs216318 −0.068 (± 0.036) .05 0.42 −0.093 (± 0.042) .03 0.26 
rs216312 −0.013 (± 0.022) .56 0.87 −0.022 (± 0.026) .41 0.60 
rs216309 −0.013 (± 0.022) .54 0.87 −0.016 (± 0.026) .53 0.60 
rs216801 −0.013 (± 0.022) .54 0.87 0.006 (± 0.026) .83 0.69 
rs7298566 −0.025 (± 0.030) .39 0.87 −0.023 (± 0.035) .52 0.59 
rs216855 0.002 (± 0.023) .94 0.90 −0.004 (± 0.028) .88 0.70 
rs917857 −0.009 (± 0.021) .66 0.89 −0.036 (± 0.025) .15 0.58 
rs4764478 0.082 (± 0.026) .001 0.03 0.096 (± 0.030) .002 0.03 
rs11063961 0.027 (± 0.024) .26 0.87 0.024 (± 0.029) .41 0.60 
rs12369177 −0.007 (± 0.022) .76 0.90 0.004 (± 0.026) .88 0.70 
rs2270151 0.021 (± 0.028) .46 0.87 0.035 (± 0.034) .29 0.58 
rs2885517 −0.011 (± 0.022) .60 0.87 −0.010 (± 0.026) .70 0.69 
rs12580835 −0.014 (± 0.022) .52 0.87 −0.019 (± 0.026) .47 0.59 
rs12367467 0.037 (± 0.034) .28 0.87 0.030 (± 0.041) .46 0.60 
SNP IDVWF:Ag levels (± SE)PqVWF:CB activity (± SE)Pq
rs10849385 −0.003 (± 0.022) .88 0.90 0.008 (± 0.026) .76 0.70 
rs7306706 −0.043 (± 0.021) .04 0.42 −0.037 (± 0.025) .14 0.58 
rs1610056 −0.004 (± 0.032) .90 0.90 −0.001 (± 0.038) .98 0.74 
rs2238103 −0.012 (± 0.022) .59 0.87 −0.027 (± 0.026) .32 0.58 
rs1800378 0.019 (± 0.022) .39 0.87 0.033 (± 0.026) .21 0.58 
rs7139057 −0.014 (± 0.027) .60 0.87 −0.035 (± 0.032) .27 0.58 
rs216293 0.005 (± 0.022) .81 0.90 −0.011 (± 0.026) .66 0.70 
rs1063857 0.039 (± 0.022) .08 0.48 0.030 (± 0.027) .26 0.58 
rs216340 0.004 (± 0.026) .87 0.90 −0.007 (± 0.031) .82 0.70 
rs12810426 0.004 (± 0.025) .88 0.90 −0.037 (± 0.030) .22 0.58 
rs216318 −0.068 (± 0.036) .05 0.42 −0.093 (± 0.042) .03 0.26 
rs216312 −0.013 (± 0.022) .56 0.87 −0.022 (± 0.026) .41 0.60 
rs216309 −0.013 (± 0.022) .54 0.87 −0.016 (± 0.026) .53 0.60 
rs216801 −0.013 (± 0.022) .54 0.87 0.006 (± 0.026) .83 0.69 
rs7298566 −0.025 (± 0.030) .39 0.87 −0.023 (± 0.035) .52 0.59 
rs216855 0.002 (± 0.023) .94 0.90 −0.004 (± 0.028) .88 0.70 
rs917857 −0.009 (± 0.021) .66 0.89 −0.036 (± 0.025) .15 0.58 
rs4764478 0.082 (± 0.026) .001 0.03 0.096 (± 0.030) .002 0.03 
rs11063961 0.027 (± 0.024) .26 0.87 0.024 (± 0.029) .41 0.60 
rs12369177 −0.007 (± 0.022) .76 0.90 0.004 (± 0.026) .88 0.70 
rs2270151 0.021 (± 0.028) .46 0.87 0.035 (± 0.034) .29 0.58 
rs2885517 −0.011 (± 0.022) .60 0.87 −0.010 (± 0.026) .70 0.69 
rs12580835 −0.014 (± 0.022) .52 0.87 −0.019 (± 0.026) .47 0.59 
rs12367467 0.037 (± 0.034) .28 0.87 0.030 (± 0.041) .46 0.60 

VWF:Ag levels and VWF:CB activity in IU/mL (± SE): an estimated change in level per minor allele. Data in the table are adjusted for age, sex, case status, blood group, hormone use, and time of blood sampling after the event.

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