Table 6

PBSC mobilization study*

PBSC mobilization procedure3 CHOP (lenograstim 10 μg/kg)3 CHOP + 3 fludarabine (lenograstim 10 μg/kg)3 CHOP + 3 fludarabine + DHAP (lenograstim 150 μg/m2)
Patients (N = 145) 36 50 59 
Success (CD34 > 2 × 106/kg) 33 (91.66%) 30 (60%) 50 (84.74%) 
    1 mobilization 29 15 48 
    2 mobilizations 4 15 2 
Failure (CD34 < 2 × 106/kg) 3 (8.33%) 20 (40%) 9 (15.25%) 
Median (CD34 × 106/kg)† 3.30 (2.56-4.33) 1.77 (1.06-3.30) 5.10 (3.50-7.97) 
PBSC mobilization procedure3 CHOP (lenograstim 10 μg/kg)3 CHOP + 3 fludarabine (lenograstim 10 μg/kg)3 CHOP + 3 fludarabine + DHAP (lenograstim 150 μg/m2)
Patients (N = 145) 36 50 59 
Success (CD34 > 2 × 106/kg) 33 (91.66%) 30 (60%) 50 (84.74%) 
    1 mobilization 29 15 48 
    2 mobilizations 4 15 2 
Failure (CD34 < 2 × 106/kg) 3 (8.33%) 20 (40%) 9 (15.25%) 
Median (CD34 × 106/kg)† 3.30 (2.56-4.33) 1.77 (1.06-3.30) 5.10 (3.50-7.97) 
*

The best results were observed after DHAP (P = .003 vs fludarabine; P < .0001 vs CHOP), whereas mobilization after CHOP was significantly better than after fludarabine (P = .001).

†

(Q1-Q3) collected at first mobilization.

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