β-globin haplotype and incidence of stroke and validated in the SWiTCH and HUSTLE cohorts
| β-globin haplotype . | HUSTLE (n = 206), % . | SWiTCH (n = 260), % . | Overall (n = 466), % . | P . | Odds ratio . | 95% CI . |
|---|---|---|---|---|---|---|
| Benin | 60.7 | 57.7 | 59.0 | .569 | 0.88 | 0.61-1.29 |
| Central African Republic (Bantu) | 19.9 | 24.2 | 22.3 | .313 | 1.29 | 0.83-2.01 |
| Senegal | 8.7 | 10.0 | 9.4 | .750 | 1.16 | 0.62-2.18 |
| Cameroon | 4.4 | 3.1 | 3.7 | .468 | 0.69 | 0.26-1.84 |
| Atypical | 6.3 | 5.0 | 5.6 | .549 | 0.78 | 0.35-1.73 |
| β-globin haplotype . | HUSTLE (n = 206), % . | SWiTCH (n = 260), % . | Overall (n = 466), % . | P . | Odds ratio . | 95% CI . |
|---|---|---|---|---|---|---|
| Benin | 60.7 | 57.7 | 59.0 | .569 | 0.88 | 0.61-1.29 |
| Central African Republic (Bantu) | 19.9 | 24.2 | 22.3 | .313 | 1.29 | 0.83-2.01 |
| Senegal | 8.7 | 10.0 | 9.4 | .750 | 1.16 | 0.62-2.18 |
| Cameroon | 4.4 | 3.1 | 3.7 | .468 | 0.69 | 0.26-1.84 |
| Atypical | 6.3 | 5.0 | 5.6 | .549 | 0.78 | 0.35-1.73 |
Abbreviations for the β-globin haplotypes are as follows: BEN for Benin, SEN for Senegal, CAR for the Central African Republic (Bantu), CAM for Cameroon, and Atypical for any haplotype differing from the classical haplotypes.